TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
84
|
390 |
MYC |
P01106
|
MYC proto-oncogene, bHLH transcription factor
|
Transcription factor
|
1.00 |
0.344 |
0.923 |
6
|
8 |
IRF3 |
Q14653
|
interferon regulatory factor 3
|
Transcription factor
|
1.2E-04 |
0.517 |
0.808 |
3
|
2 |
SF3B1 |
O75533
|
splicing factor 3b subunit 1
|
Nucleic acid binding
|
1.00 |
0.511 |
0.731 |
8
|
9 |
CRNKL1 |
Q9BZJ0
|
crooked neck pre-mRNA splicing factor 1
|
Nucleic acid binding
|
2.7E-06 |
0.711 |
0.385 |
2
|
1 |
BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
125
|
84 |
MTOR |
P42345
|
mechanistic target of rapamycin kinase
|
Kinase
|
1.00 |
0.343 |
0.885 |
86
|
26 |
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
85
|
55 |
RAF1 |
P04049
|
Raf-1 proto-oncogene, serine/threonine kinase
|
Kinase
|
0.85 |
0.418 |
0.885 |
45
|
26 |
MAP2K1 |
Q02750
|
mitogen-activated protein kinase kinase 1
|
Kinase
|
0.90 |
0.439 |
0.846 |
26
|
30 |
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
23
|
28 |
KIT |
P10721
|
KIT proto-oncogene, receptor tyrosine kinase
|
Kinase
|
0.98 |
0.366 |
0.808 |
21
|
66 |
PIK3R1 |
P27986
|
phosphoinositide-3-kinase regulatory subunit 1
|
Kinase
|
1.00 |
0.477 |
0.885 |
10
|
24 |
MAP2K2 |
P36507
|
mitogen-activated protein kinase kinase 2
|
Kinase
|
0.97 |
0.534 |
0.731 |
8
|
15 |
CDK4 |
P11802
|
cyclin dependent kinase 4
|
Kinase
|
6.3E-02 |
0.412 |
0.808 |
7
|
2 |
ARAF |
P10398
|
A-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
0.96 |
0.619 |
0.654 |
3
|
2 |
B2M |
P61769
|
beta-2-microglobulin
|
Immune response
|
0.56 |
0.447 |
0.846 |
12
|
6 |
EZH2 |
Q15910
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
Epigenetic regulator
|
1.00 |
0.376 |
0.885 |
6
|
16 |
HRAS |
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
8.0E-02 |
0.378 |
0.885 |
71
|
21 |
KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
66
|
35 |
GNAS |
O95467 P63092 P84996 Q5JWF2
|
GNAS complex locus
|
Enzyme modulator
|
0.68 |
0.420 |
0.885 |
60
|
27 |
NRAS |
P01111
|
NRAS proto-oncogene, GTPase
|
Enzyme modulator
|
0.49 |
0.390 |
0.808 |
37
|
14 |
FBXW7 |
Q969H0
|
F-box and WD repeat domain containing 7
|
Enzyme modulator
|
1.00 |
0.465 |
0.808 |
18
|
7 |
GNA11 |
P29992
|
G protein subunit alpha 11
|
Enzyme modulator
|
0.89 |
0.563 |
0.731 |
5
|
8 |