Source: GWASDB

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 11 61
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 9 7
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 7 6
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 6 4
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 5 3
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 4 4
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 4 4
IL6 P05231 interleukin 6 0.32 0.248 0.962 3 1
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 2 3
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1 6
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 1 1
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1 1
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962 1 1
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 18 140
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923 8 97
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 7 16
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 7 203
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 6 2
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 5 7
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 5 4
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 5 9
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923 5 2
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 4 5
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 4 2