Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923 72
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 64
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 39
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 34
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 31
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 27
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 24
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 19
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808 17
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808 13
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846 9
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 8
MTA1 Q13330 metastasis associated 1 Nucleic acid binding 1.00 0.547 0.692 7
COL4A5 P29400 collagen type IV alpha 5 chain 1.00 0.553 0.654 5
EPHA4 P54764 EPH receptor A4 Kinase 1.00 0.566 0.846 5
DICER1 Q9UPY3 dicer 1, ribonuclease III Enzyme 1.00 0.446 0.846 5
RRM1 P23921 ribonucleotide reductase catalytic subunit M1 Enzyme 1.00 0.552 0.692 4
CSMD1 Q96PZ7 CUB and Sushi multiple domains 1 1.00 0.610 0.500 4
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 3
ACIN1 Q9UKV3 apoptotic chromatin condensation inducer 1 1.00 0.751 0.308 1
USP7 Q93009 ubiquitin specific peptidase 7 Enzyme 1.00 0.538 0.808 1
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 53
IGF2BP3 O00425 insulin like growth factor 2 mRNA binding protein 3 Enzyme 1.00 0.570 0.577 14
CTNND1 O60716 catenin delta 1 Cellular structure 1.00 0.500 0.808 11