Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
XRCC5 P13010 X-ray repair cross complementing 5 Enzyme 1.00 0.554 0.808 7
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 32
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808 11
VAV1 P15498 vav guanine nucleotide exchange factor 1 1.00 0.556 0.769 3
EFEMP1 Q12805 EGF containing fibulin extracellular matrix protein 1 Extracellular structure 1.00 0.540 0.769 5
PTK2 Q05397 protein tyrosine kinase 2 Kinase 1.00 0.497 0.808 21
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885 31
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 18
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846 35
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 34
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846 41
IL6ST P40189 interleukin 6 signal transducer Signaling 1.00 0.475 0.808 17
MEN1 O00255 menin 1 1.00 0.444 0.808 18
CFLAR O15519 CASP8 and FADD like apoptosis regulator Enzyme 1.00 0.485 0.846 24
CCNA2 P20248 cyclin A2 Enzyme modulator 1.00 0.578 0.654 11
FBXW7 Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 1.00 0.465 0.808 9
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885 24
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 61
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 71
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808 13
NTRK3 Q16288 neurotrophic receptor tyrosine kinase 3 Kinase 1.00 0.522 0.692 5
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 47
IQGAP1 P46940 IQ motif containing GTPase activating protein 1 Enzyme modulator 1.00 0.560 0.692 4
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 23