Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 16
ADRA2A P08913 adrenoceptor alpha 2A G-protein coupled receptor 8.2E-04 0.578 0.615 11
ATP5PD O75947 ATP synthase peripheral stalk subunit d Transporter 4.6E-04 0.780 0.346 4
AVPR1B P47901 arginine vasopressin receptor 1B G-protein coupled receptor 3.7E-04 0.705 0.385 7
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 17
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846 10
CHRM2 P08172 cholinergic receptor muscarinic 2 G-protein coupled receptor 0.18 0.585 0.615 1
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 15
CRHBP P24387 corticotropin releasing hormone binding protein Signaling 0.21 0.659 0.500 3
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769 8
CRHR2 Q13324 corticotropin releasing hormone receptor 2 G-protein coupled receptor 8.5E-17 0.584 0.731 10
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923 4
CYP2D7 A0A087X1C5 cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) 0.659 0.577 1
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 24
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846 7
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808 16
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 23
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 25
FADD Q13158 Fas associated via death domain 0.53 0.537 0.846 14
GATA1 P15976 GATA binding protein 1 0.95 0.483 0.808 1
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 26
HDAC5 Q9UQL6 histone deacetylase 5 Epigenetic regulator 1.00 0.552 0.769 7