Source: HPO

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
RAD51D O75771 RAD51 paralog D 1.1E-09 0.674 0.385 7
RAD54L Q92698 RAD54 like 2.4E-15 0.633 0.423 3
NQO2 P16083 N-ribosyldihydronicotinamide:quinone reductase 2 8.8E-07 0.628 0.500 2
AAGAB Q6PD74 alpha and gamma adaptin binding protein 3.9E-07 0.695 0.538 12
BARD1 Q99728 BRCA1 associated RING domain 1 1.4E-24 0.597 0.538 8
RB1CC1 Q8TDY2 RB1 inducible coiled-coil 1 1.00 0.653 0.538 2
RNF43 Q68DV7 ring finger protein 43 0.73 0.584 0.577 13
PALLD Q8WX93 palladin, cytoskeletal associated protein 5.3E-06 0.628 0.615 26
NTHL1 P78549 nth like DNA glycosylase 1 Enzyme 5.7E-10 0.623 0.615 15
COL14A1 Q05707 collagen type XIV alpha 1 chain Receptor 1.4E-14 0.674 0.615 8
HMMR O75330 hyaluronan mediated motility receptor 5.5E-21 0.544 0.615 2
KLLN B2CW77 killin, p53 regulated DNA replication inhibitor 5.1E-03 0.578 0.654 57
OPCML Q14982 opioid binding protein/cell adhesion molecule like 0.23 0.606 0.654 5
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692 116
SEC23B Q15437 SEC23 homolog B, COPII coat complex component Enzyme modulator 6.1E-20 0.579 0.692 65
SLC22A18 Q96BI1 solute carrier family 22 member 18 Transporter 6.5E-06 0.595 0.692 4
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731 106
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731 77
POLE Q07864 DNA polymerase epsilon, catalytic subunit 8.0E-27 0.526 0.731 48
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769 134
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769 33
XRCC3 O43542 X-ray repair cross complementing 3 1.9E-10 0.505 0.769 2
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 301
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808 173