Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CIB1 Q99828 calcium and integrin binding 1 3.3E-04 0.458 0.769 1
IL33 O95760 interleukin 33 8.3E-10 0.409 0.885 1
SYP P08247 synaptophysin Transporter 0.92 0.481 0.808 1
DNM1 Q05193 dynamin 1 Enzyme modulator 1.00 0.595 0.692 2
INS-IGF2 F8WCM5 INS-IGF2 readthrough 5.6E-02 0.633 0.500 2
ADAM9 Q13443 ADAM metallopeptidase domain 9 Enzyme 2.9E-02 0.560 0.654 3
APLP2 Q06481 amyloid beta precursor like protein 2 Enzyme modulator 0.38 0.659 0.462 3
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808 3
PLCB1 Q9NQ66 phospholipase C beta 1 Enzyme 0.98 0.595 0.654 3
BCL2L2 Q92843 BCL2 like 2 Signaling 0.47 0.599 0.615 4
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846 4
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923 5
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769 5
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808 6
IDE P14735 insulin degrading enzyme Enzyme 6.6E-03 0.604 0.577 6
NGB Q9NPG2 neuroglobin Transporter 4.5E-03 0.631 0.462 6
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846 7
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846 8
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808 9
MAP2 P11137 microtubule associated protein 2 1.00 0.537 0.692 9
MT2A P02795 metallothionein 2A 1.2E-05 0.553 0.808 9
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769 10
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846 10
GAPDH P04406 glyceraldehyde-3-phosphate dehydrogenase Enzyme 0.11 0.447 0.808 10