Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 58
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 5
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 59
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 69
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 17
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846 17
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 18
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 8
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 24
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885 10
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885 3
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885 30
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923 20
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846 6
ARSA P15289 arylsulfatase A Enzyme 1.1E-11 0.448 0.923 1
ANXA2 P07355 annexin A2 9.8E-05 0.453 0.808 5
GPX1 P07203 glutathione peroxidase 1 Enzyme 3.9E-05 0.458 0.923 13
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769 8
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846 13
GSN P06396 gelsolin Cellular structure 3.9E-11 0.475 0.885 4
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769 4