Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846 399 37
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 393 25
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885 380 935
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 366 651
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808 356 60
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846 351 37
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846 350 56
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885 347 73
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 345 48
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769 340 21
CDC42 P60953 cell division cycle 42 Enzyme modulator 0.79 0.458 0.846 327 16
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808 320 266
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769 320 106
FOXP1 Q9H334 forkhead box P1 1.00 0.460 0.808 317 64
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846 315 37
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808 314 21
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808 306 19
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808 297 261
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808 296 24
NHS Q6T4R5 NHS actin remodeling regulator 1.00 0.466 0.846 295 26
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808 292 110
ACTG1 P63261 actin gamma 1 Cellular structure 4.8E-03 0.477 0.846 291 20
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808 289 8
LRP5 O75197 LDL receptor related protein 5 0.51 0.485 0.846 283 99