Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TLR1 Q15399 toll like receptor 1 5.9E-23 0.496 0.808 4 27
CYP27A1 Q02318 cytochrome P450 family 27 subfamily A member 1 Enzyme 5.3E-19 0.538 0.731 3 1
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 37 18
FAM13A O94988 family with sequence similarity 13 member A 1.9E-18 0.653 0.462 10 12
NOD1 Q9Y239 nucleotide binding oligomerization domain containing 1 Enzyme 2.5E-18 0.541 0.769 3 1
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923 5 2
PER3 P56645 period circadian regulator 3 Transcription factor 1.4E-17 0.559 0.731 3 2
CABIN1 Q9Y6J0 calcineurin binding protein 1 Enzyme modulator 3.3E-17 0.536 0.846 2 1
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808 12 32
MSRA Q9UJ68 methionine sulfoxide reductase A Enzyme 1.5E-15 0.608 0.615 6 7
TTC39B Q5VTQ0 tetratricopeptide repeat domain 39B 2.2E-15 0.890 0.154 5 4
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731 2 1
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 4 4
FDFT1 P37268 farnesyl-diphosphate farnesyltransferase 1 4.1E-15 0.621 0.615 3 2
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 2 1
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846 10 18
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885 2 1
MADD Q8WXG6 MAP kinase activating death domain 1.5E-14 0.644 0.538 7 12
ADGRD1 Q6QNK2 adhesion G protein-coupled receptor D1 G-protein coupled receptor 2.5E-14 0.861 0.077 4 4
VIL1 P09327 villin 1 Cellular structure 2.6E-14 0.691 0.423 3 3
PLCD4 Q9BRC7 phospholipase C delta 4 Enzyme 1.3E-13 0.861 0.154 2 2
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846 9 34
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846 6 1
AMPD3 Q01432 adenosine monophosphate deaminase 3 Enzyme 1.1E-12 0.743 0.385 9 7