Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 85
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 79
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 77
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 73
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 67
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 66
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846 66
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 65
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 65
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885 64
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 59
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923 58
CDH1 P12830 cadherin 1 0.15 0.401 0.808 57
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885 56
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 53
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 53
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 53
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 53
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923 52
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 48
JUN P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 6.0E-02 0.442 0.885 46
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 46
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808 45
CYP2A6 P11509 cytochrome P450 family 2 subfamily A member 6 5.4E-09 0.556 0.731 44