Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 703 681
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 687 4
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 679 23
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 666 9
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 646 11
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 644 54
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 587 9
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923 586 34
MBL2 P11226 mannose binding lectin 2 Receptor 2.7E-03 0.390 0.846 563 21
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846 559 31
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923 551 52
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 551 8
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846 528 10
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846 526 2
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885 519 77
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846 519 41
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 508 15
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885 498 158
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 496 29
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885 490 42
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 487 9
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846 485 114
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 473 24