Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 341 22
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769 340 21
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 339 239
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885 335 6
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808 320 266
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 317 18
NF2 P35240 neurofibromin 2 1.00 0.468 0.885 312 54
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808 306 19
DICER1 Q9UPY3 dicer 1, ribonuclease III Enzyme 1.00 0.446 0.846 302 191
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692 300 17
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808 292 110
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769 289 35
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846 288 1
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808 287 533
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 284 42
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846 283 23
COL4A1 P02462 collagen type IV alpha 1 chain 1.00 0.484 0.731 277 62
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808 261 41
HDAC4 P56524 histone deacetylase 4 Epigenetic regulator 1.00 0.484 0.885 256 9
USP9X Q93008 ubiquitin specific peptidase 9 X-linked 1.00 0.502 0.846 255 14
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769 252 23
SMC1A Q14683 structural maintenance of chromosomes 1A 1.00 0.509 0.808 251 53
TRPS1 Q9UHF7 transcriptional repressor GATA binding 1 1.00 0.537 0.769 248 82
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846 245 6