Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 85
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 77
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 77
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 76
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 76
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 76
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846 74
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 73
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 72
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 66
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 66
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808 66
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846 66
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 64
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 62
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 60
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 59
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 58
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923 58
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846 57
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885 57
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 57
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885 56
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 56