Source: HPO

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
RNF168 Q8IYW5 ring finger protein 168 2.1E-13 0.653 0.731 46
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885 45
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923 43
POLA1 P09884 DNA polymerase alpha 1, catalytic subunit 1.00 0.653 0.731 43
CCDC114 Q96M63 coiled-coil domain containing 114 6.6E-09 0.674 0.500 42
CYBA P13498 cytochrome b-245 alpha chain 8.9E-06 0.520 0.769 42
KCNJ6 P48051 potassium inwardly rectifying channel subfamily J member 6 Ion channel 0.54 0.615 0.692 42
NCF1 P14598 neutrophil cytosolic factor 1 2.8E-05 0.521 0.808 41
NCF2 P19878 neutrophil cytosolic factor 2 Enzyme 4.0E-07 0.601 0.692 41
GAS8 O95995 growth arrest specific 8 1.1E-12 0.636 0.654 39
IGHM P01871 immunoglobulin heavy constant mu 0.644 0.654 39
TNFRSF13B O14836 TNF receptor superfamily member 13B 2.1E-15 0.558 0.769 38
CD79B P40259 CD79b molecule Receptor 0.92 0.576 0.577 37
CR2 P20023 complement C3d receptor 2 4.7E-19 0.556 0.654 37
BLNK Q8WV28 B cell linker Signaling 0.61 0.603 0.731 36
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923 36
ICOS Q9Y6W8 inducible T cell costimulator 3.1E-02 0.502 0.731 36
CD19 P15391 CD19 molecule 0.90 0.430 0.885 35
TNFRSF13C Q96RJ3 TNF receptor superfamily member 13C 0.27 0.540 0.731 35
IGLL1 P15814 immunoglobulin lambda like polypeptide 1 1.4E-02 0.678 0.538 34
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731 32
P4HTM Q9NXG6 prolyl 4-hydroxylase, transmembrane 3.9E-09 0.666 0.500 30
CD247 P20963 CD247 molecule 1.7E-02 0.539 0.731 29
FCGR2A P12318 Fc fragment of IgG receptor IIa Cell adhesion 2.0E-06 0.480 0.769 28