Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1801 22
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1314 146
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 1049 62
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 933 59
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 722 24
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 703 97
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 687 4
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 684 974
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 679 45
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 675 21
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 674 3
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 656 3066
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 653 35
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 646 11
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 627 9
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 616 11
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 487 9
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 412 38
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846 369 155
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 366 651
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846 363 16