Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 169
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 118
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 95
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 86
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 77
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 53
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 47
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 39
TIMP2 P16035 TIMP metallopeptidase inhibitor 2 Enzyme modulator 0.79 0.425 0.846 37
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923 18
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808 18
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 9
KIF14 Q15058 kinesin family member 14 Cellular structure 4.1E-05 0.578 0.654 7
MAGEA4 P43358 MAGE family member A4 Cell adhesion 0.653 0.346 7
MTA1 Q13330 metastasis associated 1 Nucleic acid binding 1.00 0.547 0.692 7
MAGEC1 O60732 MAGE family member C1 Cell adhesion 8.0E-02 0.792 0.308 4
NUDT1 P36639 nudix hydrolase 1 Enzyme 7.4E-12 0.597 0.769 4
PRG1 p53-responsive gene 1 0.839 0.231 2
PYGB P11216 glycogen phosphorylase B Enzyme 1.4E-14 0.792 0.308 2
CTAG1A P78358 cancer/testis antigen 1A 0.508 0.731 1