×
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
Non-Small Cell Lung Carcinoma
0.700
AlteredExpression
LHGDN
The present study suggests that increased expression of erbB3 may play an additional role in NSCLC especially in female, nonsmoker, adenocarcinoma, and with EGFR gene mutation.
17631905 2008
×
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
Non-Small Cell Lung Carcinoma
0.700
GeneticVariation
LHGDN
Exogenous expression of either the L858R point mutant or the DeltaE746-E750 deletion mutant form of EGFR in immortalized human bronchial epithelial cells, p53 WT NSCLC (A549 ), or p53-null NSCLC (NCI-H1299 ) resulted in dramatically increased sensitivity to IR.
17018617 2006
×
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
Non-Small Cell Lung Carcinoma
0.700
GeneticVariation
LHGDN
Race, gender and mutations in the prediction of anti-EGFR activity.
16555991 2005
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Non-Small Cell Lung Carcinoma
0.700
GeneticVariation
LHGDN
P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma.
15112277 2004
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Non-Small Cell Lung Carcinoma
0.400
GeneticVariation
LHGDN
K-RAS and P53 mutations in association with COX-2 and hTERT expression and clinico-pathological status of NSCLC patients.
18957720 2008
×
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2
Non-Small Cell Lung Carcinoma
0.100
Biomarker
LHGDN
MMP-2 and TIMP-2 were expressed in high rates in NSCLC but CD44v6 expression was about 50%.
18265895 2008
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Non-Small Cell Lung Carcinoma
0.100
Biomarker
LHGDN
MMP-2, TIMP-2 and CD44v6 expression in non-small-cell lung carcinomas.
18265895 2008
×
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
Non-Small Cell Lung Carcinoma
0.100
AlteredExpression
LHGDN
Other reports suggested that high ErbB3 protein expression was associated with shorter survival in advanced non-small-cell lung carcinomas (NSCLC ).
17631905 2008
×
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
Non-Small Cell Lung Carcinoma
0.100
Biomarker
LHGDN
MMP-2 and TIMP-2 were expressed in high rates in NSCLC but CD44v6 expression was about 50%.18265895 2008
×
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
Non-Small Cell Lung Carcinoma
0.100
Biomarker
LHGDN
The results of the present study suggest that PPARgamma activation induces apoptotic cell death in non-small-cell lung carcinoma mainly through ROS formation via POX induction.
17535976 2007
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Non-Small Cell Lung Carcinoma
0.100
Biomarker
LHGDN
We examined four c-Met-positive non-small-cell lung cancer (NSCLC ) cell lines for effects of HGF on COX-2 .
17550984 2007
×
Entrez Id: 246100
Gene Symbol: CTAG1A
CTAG1A
Non-Small Cell Lung Carcinoma
0.100
AlteredExpression
LHGDN
MAGE-A4 and NY-ESO-1 were expressed in 40 of 141 (28.4%) and 13 of 157 (8.3%) NSCLC respectively.
16596224 2006
×
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
Non-Small Cell Lung Carcinoma
0.100
Biomarker
LHGDN
Release of bFGF following apoptosis and necrosis in NSCLC cells: effects on chemosensitivity to cisplatin.
16077988 2005
×
Entrez Id: 9112
Gene Symbol: MTA1
MTA1
Non-Small Cell Lung Carcinoma
0.100
AlteredExpression
LHGDN
Our results show that the expression of the MTA1 gene is closely related to invasiveness and metastasis in NSCLC .
11804687 2002
×
Entrez Id: 4521
Gene Symbol: NUDT1
NUDT1
Non-Small Cell Lung Carcinoma
0.050
AlteredExpression
LHGDN
Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue.
12757855 2003
×
Entrez Id: 796
Gene Symbol: CALCA
CALCA
Non-Small Cell Lung Carcinoma
0.030
Biomarker
LHGDN
Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway.
18626012 2008
×
Entrez Id: 4103
Gene Symbol: MAGEA4
MAGEA4
Non-Small Cell Lung Carcinoma
0.030
AlteredExpression
LHGDN
Expression of the MAGE-A4 and NY-ESO-1 cancer-testis antigens and T cell infiltration in non-small cell lung carcinoma and their prognostic significance.
16596224 2006
×
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
Non-Small Cell Lung Carcinoma
0.020
AlteredExpression
LHGDN
Our data showed not only that GDNF is overexpressed at the transcript level in squamous non-small-cell lung carcinoma , but also that the GDNF protein is present in early-stage lesions.
15870700 2005
×
Entrez Id: 9928
Gene Symbol: KIF14
KIF14
Non-Small Cell Lung Carcinoma
0.020
AlteredExpression
LHGDN
KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers.
15897902 2005
×
Entrez Id: 5834
Gene Symbol: PYGB
PYGB
Non-Small Cell Lung Carcinoma
0.010
AlteredExpression
LHGDN
Clinicopathological significance of BGP expression in non-small-cell lung carcinoma: relationship with histological type, microvessel density and patients' survival.
17393985 2006
×
Entrez Id: 23574
Gene Symbol: PRG1
PRG1
Non-Small Cell Lung Carcinoma
0.010
GeneticVariation
LHGDN
P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma.
15112277 2004
×
Entrez Id: 9947
Gene Symbol: MAGEC1
MAGEC1
Non-Small Cell Lung Carcinoma
0.010
AlteredExpression
LHGDN
Whereas colorectal and renal cell carcinomas, as well as sarcomas, exhibit poor or no CT7-33 staining, carcinomas of the mammary gland and ovary, nonsmall cell lung carcinoma and metastatic melanomas exhibit a high incidence of CT7 protein expression.
12115486 2002