Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TTN Q8WZ42 titin 6.4E-84 0.534 0.655 17 29
MTOR P42345 mechanistic target of rapamycin kinase kinase; nucleic acid binding; transferase 1.00 0.399 0.793 12 9
FGFR1 P11362 fibroblast growth factor receptor 1 1.00 0.388 0.759 9 44
EPHA3 P29320 EPH receptor A3 1.4E-05 0.552 0.586 6 2
TRRAP Q9Y4A5 transformation/transcription domain associated protein kinase; nucleic acid binding; transferase 1.00 0.713 0.345 5 4
DCLK3 Q9C098 doublecortin like kinase 3 0.10 0.720 0.448 5 2
ATR Q13535 ATR serine/threonine kinase kinase; nucleic acid binding; transferase 1.7E-08 0.486 0.759 5 1
CASK O14936 calcium/calmodulin dependent serine protein kinase cell junction protein; kinase; transferase 1.00 0.584 0.517 4 4
NTRK3 Q16288 neurotrophic receptor tyrosine kinase 3 1.00 0.547 0.586 4 1
TRPM6 Q9BX84 transient receptor potential cation channel subfamily M member 6 receptor; transporter 9.6E-10 0.707 0.448 4 1
MYO18B Q8IUG5 myosin XVIIIB 2.6E-30 0.681 0.448 4 0
BTK Q06187 Bruton tyrosine kinase 1.00 0.524 0.690 3 23
EPHA5 P54756 EPH receptor A5 3.1E-05 0.743 0.241 3 1
NEK1 Q96PY6 NIMA related kinase 1 7.0E-25 0.619 0.621 3 1
BRSK1 Q8TDC3 BR serine/threonine kinase 1 kinase; transferase 1.00 0.799 0.276 3 1
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.00 0.475 0.690 3 0
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase 1.5E-69 0.493 0.759 3 0
CDC42BPB Q9Y5S2 CDC42 binding protein kinase beta kinase; transferase 1.00 0.773 0.310 3 0
WNK3 Q9BYP7 WNK lysine deficient protein kinase 3 kinase; transferase 1.00 0.815 0.241 3 0
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 4.6E-12 0.624 0.414 3 0
DDR2 Q16832 discoidin domain receptor tyrosine kinase 2 0.88 0.579 0.621 2 4
TTBK1 Q5TCY1 tau tubulin kinase 1 kinase; transferase 1.00 0.815 0.207 2 1
CAMK4 Q16566 calcium/calmodulin dependent protein kinase IV cytoskeletal protein; kinase; transferase 0.51 0.659 0.621 2 0
LATS1 O95835 large tumor suppressor kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 1.00 0.602 0.379 2 0