Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 992 56
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 506 3
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885 449 66
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846 409 88
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808 303 20
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885 260 7
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808 231 74
POR P16435 cytochrome p450 oxidoreductase 3.4E-10 0.502 0.769 218 21
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769 209 39
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577 189 7
PDE5A O76074 phosphodiesterase 5A 1.1E-04 0.513 0.731 187 8
MIR137 microRNA 137 0.513 0.846 171 1
PARK7 Q99497 Parkinsonism associated deglycase Enzyme 0.75 0.535 0.808 161 15
PODXL O00592 podocalyxin like 1.0E-03 0.551 0.731 156 5
HTRA2 O43464 HtrA serine peptidase 2 3.6E-03 0.542 0.692 151 6
MC4R P32245 melanocortin 4 receptor G-protein coupled receptor 9.2E-04 0.535 0.692 149 58
CYP11B1 P15538 cytochrome P450 family 11 subfamily B member 1 8.2E-07 0.563 0.615 139 80
DNAJC6 O75061 DnaJ heat shock protein family (Hsp40) member C6 1.00 0.641 0.385 86 10
VPS13C Q709C8 vacuolar protein sorting 13 homolog C 7.6E-49 0.653 0.346 71 12
CPP ceruloplasmin pseudogene 0.631 0.731 55 0
RTN2 O75298 reticulon 2 0.42 0.711 0.385 43 4