Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 27429
Gene Symbol: HTRA2
HTRA2
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 11315
Gene Symbol: PARK7
PARK7
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 7345
Gene Symbol: UCHL1
UCHL1
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 1584
Gene Symbol: CYP11B1
CYP11B1
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 6622
Gene Symbol: SNCA
SNCA
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 5071
Gene Symbol: PRKN
PRKN
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 65018
Gene Symbol: PINK1
PINK1
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 9829
Gene Symbol: DNAJC6
DNAJC6
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 54832
Gene Symbol: VPS13C
VPS13C
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 5447
Gene Symbol: POR
POR
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 6253
Gene Symbol: RTN2
RTN2
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 5420
Gene Symbol: PODXL
PODXL
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.100 Biomarker HPO

Entrez Id: 406928
Gene Symbol: MIR137
MIR137
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.010 Biomarker BEFREE Research results also displayed that the majority of circRNAs has multiple binding sites of microRNAs, including miR-137, which has been reported to be linked to FSD. 31551192

2019

Entrez Id: 8654
Gene Symbol: PDE5A
PDE5A
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.010 AlteredExpression BEFREE In western blotting, the expressions of eNOS and PDE5 were significantly lower in the FSD group than in the control group (p = 0.003 and p = 0.038 respectively). 27686568

2017

Entrez Id: 5617
Gene Symbol: PRL
PRL
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.010 Biomarker BEFREE Also FSH-LH combination and PRL were found as independent factors for FSD. 28660561

2017

Entrez Id: 340451
Gene Symbol: CPP
CPP
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.010 Biomarker BEFREE Dissatisfaction with the spouse's sexual ability, poor marital affection, sexual difficulties of the spouse, dissatisfaction with the marriage, rural life, CPP, and postmenopausal were conceivable risk factors for FSD in Beijing women. 28584199

2017

Entrez Id: 4160
Gene Symbol: MC4R
MC4R
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.010 Biomarker BEFREE Bremelanotide is an on-demand, subcutaneous melanocortin-receptor agonist that binds to the melanocortin receptor 4 and is being developed for the treatment of female sexual dysfunction. 27977473

2017

Entrez Id: 6046
Gene Symbol: BRD2
BRD2
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.010 Biomarker BEFREE Also FSH-LH combination and PRL were found as independent factors for FSD. 28660561

2017

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.010 AlteredExpression BEFREE In western blotting, the expressions of eNOS and PDE5 were significantly lower in the FSD group than in the control group (p = 0.003 and p = 0.038 respectively). 27686568

2017

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.010 GeneticVariation BEFREE This study suggested that there was no significant association between BDNF Val66Met with FSD. 27787964

2016

Entrez Id: 1815
Gene Symbol: DRD4
DRD4
CUI: C1112442
Disease: Female sexual dysfunction
Female sexual dysfunction
0.010 GeneticVariation BEFREE We could not replicate previously reported candidate SNPs associated with FSD in the DRD4, 5HT2A and IL-1B loci. 22509378

2012