Source: CTD_human

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 1.000 2 0 1994 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.500 None 0.966 3 0 1991 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.600 None 0.964 1 0 1995 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 1.000 3 0 1993 2020
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 1.000 1 0 1993 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.600 None 1.000 3 0 1997 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.979 2 0 1989 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.995 9 0 1997 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.966 1 0 1996 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.946 3 0 1996 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.500 None 0.981 6 0 1991 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.978 1 0 2005 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 1.000 1 0 1998 2020
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.957 1 0 1999 2015
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.350 None 1.000 1 0 2013 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.960 4 0 1984 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.958 4 0 2001 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.349 0.846 0.46
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 1.000 1 0 2005 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.600 None 1.000 1 0 1998 2019
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.364 0.962 3.5E-02
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.350 None 0.833 2 0 1993 2015
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.340 None 1.000 2 0 2005 2012
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
notch receptor 1 0.369 0.885 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.360 None 1.000 1 0 2009 2017
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.500 None 0.948 7 0 1992 2019
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
interleukin 1 receptor antagonist 0.373 0.923 3.1E-02
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.320 None 1.000 1 0 2005 2017
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10
C-X-C motif chemokine ligand 10 0.378 0.885 0.37
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.300 None 1.000 1 0 2004 2004