Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4160
Gene Symbol: MC4R
MC4R
melanocortin 4 receptor 0.580 0.586 9.1E-04
CUI: C0028754
Disease: Obesity
Obesity
disease 0.900 0.948 7 0 1997 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.388 0.828 0.14
CUI: C0028754
Disease: Obesity
Obesity
disease 0.900 0.968 1 0 1997 2018
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
leptin receptor 0.474 0.793 1.00
CUI: C0028754
Disease: Obesity
Obesity
disease 0.700 0.872 34 0 1979 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.400 0.793 0.39
CUI: C0028754
Disease: Obesity
Obesity
disease 0.700 0.917 28 0 1973 2018
Entrez Id: 6492
Gene Symbol: SIM1
SIM1
SIM bHLH transcription factor 1 0.701 0.345 1.00
CUI: C0028754
Disease: Obesity
Obesity
disease 0.700 1.000 2 0 1998 2016
Entrez Id: 5122
Gene Symbol: PCSK1
PCSK1
proprotein convertase subtilisin/kexin type 1 0.621 0.483 2.9E-09
CUI: C0028754
Disease: Obesity
Obesity
disease 0.700 0.944 1 0 1997 2016
Entrez Id: 5443
Gene Symbol: POMC
POMC
proopiomelanocortin 0.382 0.862 9.4E-05
CUI: C0028754
Disease: Obesity
Obesity
disease 0.700 0.940 1 0 1992 2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.432 0.828 8.2E-02
CUI: C0028754
Disease: Obesity
Obesity
disease 0.600 1.000 2 0 2008 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
adiponectin, C1Q and collagen domain containing 0.485 0.724 5.0E-09
CUI: C0028754
Disease: Obesity
Obesity
disease 0.600 0.960 2 0 1998 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.355 0.897 1.00
CUI: C0028754
Disease: Obesity
Obesity
disease 0.600 1.000 1 0 2001 2017
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
insulin receptor substrate 1 0.532 0.621 3.5E-02
CUI: C0028754
Disease: Obesity
Obesity
disease 0.600 0.943 1 0 1995 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.287 0.966 0.34
CUI: C0028754
Disease: Obesity
Obesity
disease 0.600 0.951 1 0 2001 2018
Entrez Id: 4023
Gene Symbol: LPL
LPL
lipoprotein lipase 0.504 0.724 7.2E-10
CUI: C0028754
Disease: Obesity
Obesity
disease 0.600 0.957 1 0 1993 2016
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
cannabinoid receptor 1 0.470 0.690 0.52
CUI: C0028754
Disease: Obesity
Obesity
disease 0.600 0.973 1 0 2005 2016
Entrez Id: 181
Gene Symbol: AGRP
AGRP
agouti related neuropeptide 0.652 0.586 7.0E-04
CUI: C0028754
Disease: Obesity
Obesity
disease 0.600 0.867 1 0 1997 2017
Entrez Id: 3290
Gene Symbol: HSD11B1
HSD11B1
hydroxysteroid 11-beta dehydrogenase 1 0.577 0.655 0.41
CUI: C0028754
Disease: Obesity
Obesity
disease 0.600 0.933 1 0 2000 2015
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
cytochrome P450 family 2 subfamily E member 1 0.473 0.759 3.9E-07
CUI: C0028754
Disease: Obesity
Obesity
disease 0.580 1.000 1 0 1998 2015
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.386 0.897 3.8E-02
CUI: C0028754
Disease: Obesity
Obesity
disease 0.570 1.000 1 0 2002 2017
Entrez Id: 1363
Gene Symbol: CPE
CPE
carboxypeptidase E 0.633 0.448 0.99
CUI: C0028754
Disease: Obesity
Obesity
disease 0.540 1.000 8 0 1990 2016
Entrez Id: 4889
Gene Symbol: NPY5R
NPY5R
neuropeptide Y receptor Y5 0.701 0.379 5.3E-03
CUI: C0028754
Disease: Obesity
Obesity
disease 0.540 0.750 1 0 1996 2007
Entrez Id: 2147
Gene Symbol: F2
F2
coagulation factor II, thrombin 0.466 0.793 1.1E-03
CUI: C0028754
Disease: Obesity
Obesity
disease 0.540 1.000 1 0 2008 2016
Entrez Id: 5367
Gene Symbol: PMCH
PMCH
pro-melanin concentrating hormone 0.652 0.448 0.12
CUI: C0028754
Disease: Obesity
Obesity
disease 0.530 0.667 1 0 2002 2010
Entrez Id: 3929
Gene Symbol: LBP
LBP
lipopolysaccharide binding protein 0.627 0.517 6.4E-15
CUI: C0028754
Disease: Obesity
Obesity
disease 0.530 1.000 1 0 2008 2013
Entrez Id: 2180
Gene Symbol: ACSL1
ACSL1
acyl-CoA synthetase long chain family member 1 0.685 0.310 2.9E-02
CUI: C0028754
Disease: Obesity
Obesity
disease 0.530 1.000 1 0 1992 2015
Entrez Id: 2878
Gene Symbol: GPX3
GPX3
glutathione peroxidase 3 0.575 0.586 4.3E-02
CUI: C0028754
Disease: Obesity
Obesity
disease 0.520 1.000 1 0 2001 2009