×
Entrez Id:
2520
Gene Symbol:
GAST
GAST
Malignant tumor of colon
0.400
Biomarker
CTD_human
The hyperplastic response of the fundic mucosa was increased by increasing gastrin doses; whereas, colon cancer hyperplasia was maximal at the lowest dose tested (125 micrograms/kg/day) and did not increase further with increasing doses of hormone.
3952654
1986
×
Entrez Id:
3383
Gene Symbol:
ICAM1
ICAM1
Malignant tumor of colon
0.350
Biomarker
CTD_human
It remains to be clarified what part both forms of ICAM-1 play in the course of colonic cancer , ulcerative colitis, and Crohn's disease.
7902311
1993
×
Entrez Id:
324
Gene Symbol:
APC
APC
Malignant tumor of colon
0.500
Biomarker
CTD_human
Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
7846077
1995
×
Entrez Id:
7048
Gene Symbol:
TGFBR2
TGFBR2
Malignant tumor of colon
0.500
Biomarker
CTD_human
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability.
7761852
1995
×
Entrez Id:
324
Gene Symbol:
APC
APC
Malignant tumor of colon
0.500
Biomarker
CTD_human
Genetic alterations in rat colon tumors induced by heterocyclic amines.
8608549
1996
×
Entrez Id:
5020
Gene Symbol:
OXT
OXT
Malignant tumor of colon
0.300
Therapeutic
CTD_human
Oxytocin and oxytocin-analogue F314 inhibit cell proliferation and tumor growth of rat and mouse mammary carcinomas.
8647655
1996
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
Malignant tumor of colon
0.400
Biomarker
CTD_human
Activating mutations in the beta-catenin (CTNNB1 ) gene corresponding to N-terminal phosphorylation sites in the protein have been implicated in the development of human colon cancer .
9515794
1998
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Malignant tumor of colon
0.600
Biomarker
CTD_human
Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice.
10223192
1999
×
Entrez Id:
324
Gene Symbol:
APC
APC
Malignant tumor of colon
0.500
Biomarker
CTD_human
Neonatal exposure to the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine via breast milk or directly induces intestinal tumors in multiple intestinal neoplasia mice.
10383901
1999
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant tumor of colon
0.500
Biomarker
CTD_human
ras p21 Isoprenylation inhibition induces flat colon tumors in Wistar rats.
10813127
2000
×
Entrez Id:
3458
Gene Symbol:
IFNG
IFNG
Malignant tumor of colon
0.400
Therapeutic
CTD_human
Regrowth of 5-fluorouracil-treated human colon cancer cells is prevented by the combination of interferon gamma, indomethacin, and phenylbutyrate.
10866311
2000
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Malignant tumor of colon
0.400
Biomarker
CTD_human
Increased ErbB-2 tyrosine kinase activity, MAPK phosphorylation, and cell proliferation in the prostate cancer cell line LNCaP following treatment by select pesticides.
11222871
2001
×
Entrez Id:
324
Gene Symbol:
APC
APC
Malignant tumor of colon
0.500
Biomarker
CTD_human
One dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) induces tumours in Min/+ mice by truncation mutations or LOH in the Apc gene.
12034317
2002
×
Entrez Id:
4609
Gene Symbol:
MYC
MYC
Malignant tumor of colon
0.400
Biomarker
CTD_human
Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents.
12189186
2002
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Malignant tumor of colon
0.400
Biomarker
CTD_human
Inhibitory effects of mofezolac, a cyclooxygenase-1 selective inhibitor, on intestinal carcinogenesis.
12189188
2002
×
Entrez Id:
6513
Gene Symbol:
SLC2A1
SLC2A1
Malignant tumor of colon
0.380
Biomarker
CTD_human
Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy.
11953883
2002
×
Entrez Id:
4057
Gene Symbol:
LTF
LTF
Malignant tumor of colon
0.310
Therapeutic
CTD_human
Down-regulation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced CYP1A2 expression is associated with bovine lactoferrin inhibition of MeIQx-induced liver and colon carcinogenesis in rats.
12079509
2002
×
Entrez Id:
6566
Gene Symbol:
SLC16A1
SLC16A1
Malignant tumor of colon
0.300
Biomarker
CTD_human
Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy.
11953883
2002
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant tumor of colon
0.500
Biomarker
CTD_human
Ursodeoxycholic acid inhibits Ras mutations, wild-type Ras activation, and cyclooxygenase-2 expression in colon cancer.
12839936
2003
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant tumor of colon
0.500
Biomarker
CTD_human
Expression profiling of CC531 colon carcinoma cells reveals similar regulation of beta-catenin target genes by both butyrate and aspirin.
12800193
2003
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
Malignant tumor of colon
0.400
Biomarker
CTD_human
Characterization of dysplastic aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
14507667
2003
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Malignant tumor of colon
0.400
Therapeutic
CTD_human
Our findings indicate a potentially novel strategy for the treatment of colon cancer , one that targets CK2 simultaneous with TNF-alpha administration.
12842827
2003
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Malignant tumor of colon
0.400
Biomarker
CTD_human
Our findings indicate a potentially novel strategy for the treatment of colon cancer , one that targets CK2 simultaneous with TNF-alpha administration.
12842827
2003
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
Malignant tumor of colon
0.400
Biomarker
CTD_human
Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.
12628520
2003
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
Malignant tumor of colon
0.400
Biomarker
CTD_human
Expression profiling of CC531 colon carcinoma cells reveals similar regulation of beta-catenin target genes by both butyrate and aspirin.
12800193
2003