Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 4 0 2000 2014
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 1995 1995
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 3 0 2000 2000
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 2000 2000
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 2002 2006
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
interleukin 17A 0.324 0.923 4.3E-02
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2014 2014
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2004 2004
Entrez Id: 5443
Gene Symbol: POMC
POMC
proopiomelanocortin 0.356 0.846 1.2E-04
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 1995 1995
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2014 2014
Entrez Id: 847
Gene Symbol: CAT
CAT
catalase 0.359 0.962 1.6E-10
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 1998 2007
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 2000 2000
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 1992 2002
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
high mobility group box 1 0.368 0.923 0.82
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 2009 2012
Entrez Id: 355
Gene Symbol: FAS
FAS
Fas cell surface death receptor 0.372 0.923 0.81
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2005 2005
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
interleukin 1 receptor antagonist 0.373 0.923 3.1E-02
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 1991 2010
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 1998 2009
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
superoxide dismutase 1 0.379 0.962 0.18
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 1998 1998
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
glutathione S-transferase pi 1 0.383 0.923 1.4E-02
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2004 2004
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
galectin 3 0.392 0.846 2.3E-05
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2012 2012
Entrez Id: 196
Gene Symbol: AHR
AHR
aryl hydrocarbon receptor 0.410 0.923 1.00
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2015 2015
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
O-6-methylguanine-DNA methyltransferase 0.412 0.885 1.2E-07
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2011 2011
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CD40 ligand 0.414 0.846 0.72
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2012 2012
Entrez Id: 351
Gene Symbol: APP
APP
amyloid beta precursor protein 0.422 0.846 4.7E-02
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2011 2011
Entrez Id: 1756
Gene Symbol: DMD
DMD
dystrophin 0.423 0.923 1.00
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2013 2013
Entrez Id: 613
Gene Symbol: BCR
BCR
BCR activator of RhoGEF and GTPase 0.431 0.885 0.99
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2013 2013