Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 4 0 2000 2014
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 3 0 2000 2000
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 2000 2000
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
interleukin 1 receptor antagonist 0.373 0.923 3.1E-02
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 1991 2010
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 1992 2002
Entrez Id: 847
Gene Symbol: CAT
CAT
catalase 0.359 0.962 1.6E-10
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 1998 2007
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
cytochrome P450 family 2 subfamily E member 1 0.459 0.885 8.1E-09
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 2002 2003
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 1998 2009
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 2000 2000
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
high mobility group box 1 0.368 0.923 0.82
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 2009 2012
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 2 0 2002 2006
Entrez Id: 613
Gene Symbol: BCR
BCR
BCR activator of RhoGEF and GTPase 0.431 0.885 0.99
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2013 2013
Entrez Id: 5950
Gene Symbol: RBP4
RBP4
retinol binding protein 4 0.493 0.808 0.52
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2012 2012
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
prion protein 0.445 0.923 6.3E-04
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2008 2008
Entrez Id: 5443
Gene Symbol: POMC
POMC
proopiomelanocortin 0.356 0.846 1.2E-04
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 1995 1995
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2014 2014
Entrez Id: 468
Gene Symbol: ATF4
ATF4
activating transcription factor 4 0.507 0.769 1.6E-02
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2004 2004
Entrez Id: 998
Gene Symbol: CDC42
CDC42
cell division cycle 42 0.458 0.846 0.79
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2009 2009
Entrez Id: 6418
Gene Symbol: SET
SET
SET nuclear proto-oncogene 0.507 0.808 1.00
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2014 2014
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
superoxide dismutase 1 0.379 0.962 0.18
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 1998 1998
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
nuclear receptor subfamily 1 group H member 4 0.513 0.808 9.4E-04
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2019 2019
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CD40 ligand 0.414 0.846 0.72
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2012 2012
Entrez Id: 9474
Gene Symbol: ATG5
ATG5
autophagy related 5 0.462 0.885 0.98
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2010 2010
Entrez Id: 9131
Gene Symbol: AIFM1
AIFM1
apoptosis inducing factor mitochondria associated 1 0.527 0.769 1.00
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2006 2006
Entrez Id: 831
Gene Symbol: CAST
CAST
calpastatin 0.541 0.846 4.1E-12
CUI: C0027540
Disease: Necrosis
Necrosis
phenotype 0.300 None 1.000 1 0 2007 2007