×
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
Necrosis
0.300
Therapeutic
CTD_human
Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis.
30996006 2019
×
Entrez Id: 112724
Gene Symbol: RDH13
RDH13
Necrosis
0.300
Biomarker
CTD_human
Retinol dehydrogenase 13 deficiency diminishes carbon tetrachloride-induced liver fibrosis in mice.
27865848 2017
×
Entrez Id: 2597
Gene Symbol: GAPDH
GAPDH
Necrosis
0.300
Therapeutic
CTD_human
GAPDH-knockdown reduce rotenone-induced H9C2 cells death via autophagy and anti-oxidative stress pathway.
25725130 2015
×
Entrez Id: 196
Gene Symbol: AHR
AHR
Necrosis
0.300
Biomarker
CTD_human
Aryl hydrocarbon receptor is necessary to protect fetal human pulmonary microvascular endothelial cells against hyperoxic injury: Mechanistic roles of antioxidant enzymes and RelB.
25831079 2015
×
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Necrosis
0.300
Therapeutic
CTD_human
Nrf2 protects against furosemide-induced hepatotoxicity.
24813929 2014
×
Entrez Id: 6418
Gene Symbol: SET
SET
Necrosis
0.300
Biomarker
CTD_human
Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis , cisplatin sensitivity and lymph node metastasis in xenograft tumor models.
24555657 2014
×
Entrez Id: 406967
Gene Symbol: MIR192
MIR192
Necrosis
0.300
Biomarker
CTD_human
Urinary microRNA profiling for identification of biomarkers after cisplatin-induced kidney injury.
24880025 2014
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Necrosis
0.300
Biomarker
CTD_human
Nonetheless, WT MEF were more sensitive to TNF α-induced death which was attributed to necrosis .
24548419 2014
×
Entrez Id: 26762
Gene Symbol: HAVCR1
HAVCR1
Necrosis
0.300
Biomarker
CTD_human
Urinary microRNA profiling for identification of biomarkers after cisplatin-induced kidney injury.
24880025 2014
×
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Necrosis
0.300
Biomarker
CTD_human
Interleukin-17 mediates triptolide-induced liver injury in mice.
24949944 2014
×
Entrez Id: 1756
Gene Symbol: DMD
DMD
Necrosis
0.300
Biomarker
CTD_human
Resveratrol decreases inflammation and increases utrophin gene expression in the mdx mouse model of Duchenne muscular dystrophy.
22795790 2013
×
Entrez Id: 1489
Gene Symbol: CTF1
CTF1
Necrosis
0.300
Therapeutic
CTD_human
Cardiotrophin-1 administration prevents the renal toxicity of iodinated contrast media in rats.
23335628 2013
×
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
Necrosis
0.300
Biomarker
CTD_human
Lack of the matricellular protein SPARC (secreted protein, acidic and rich in cysteine) attenuates liver fibrogenesis in mice.
23408952 2013
×
Entrez Id: 613
Gene Symbol: BCR
BCR
Necrosis
0.300
Biomarker
CTD_human
Disrupting BCR-ABL in combination with secondary leukemia-specific pathways in CML cells leads to enhanced apoptosis and decreased proliferation.
23211037 2013
×
Entrez Id: 384
Gene Symbol: ARG2
ARG2
Necrosis
0.300
Biomarker
CTD_human
In contrast to prostate cancer, ARG2 expression was rarely demonstrated in PDC cells by immunohistochemistry, and instead ARG2 was characteristically expressed in α-smooth muscle actin-positive cancer-associated fibroblasts (CAFs), especially those located within and around necrotic areas in PDC.
23424623 2013
×
Entrez Id: 2628
Gene Symbol: GATM
GATM
Necrosis
0.300
Biomarker
CTD_human
Integrated transcriptomic and proteomic evaluation of gentamicin nephrotoxicity in rats.
22061828 2012
×
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
Necrosis
0.300
Biomarker
CTD_human
The inhibition of c-Jun N-terminal Kinase and p38 attenuated CD154 -mediated apoptosis but not necrosis .
22295117 2012
×
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
Necrosis
0.300
Biomarker
CTD_human
Immunohistochemical analysis showed that Gal-3 was predominantly expressed by mononuclear cells infiltrating into necrotic areas.
22461450 2012
×
Entrez Id: 5950
Gene Symbol: RBP4
RBP4
Necrosis
0.300
Biomarker
CTD_human
Integrated transcriptomic and proteomic evaluation of gentamicin nephrotoxicity in rats.
22061828 2012
×
Entrez Id: 6915
Gene Symbol: TBXA2R
TBXA2R
Necrosis
0.300
Biomarker
CTD_human
Thromboxane A(2) receptor signaling promotes liver tissue repair after toxic injury through the enhancement of macrophage recruitment.
22206755 2012
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Necrosis
0.300
Biomarker
CTD_human
TNF -α treatment of primary human lung epithelia and A549 cells induced ZIP8 expression, resulting in significantly higher cell death attributable to both apoptosis and necrosis following Cd exposure.22345571 2012
×
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
Necrosis
0.300
Biomarker
CTD_human
High mobility group box 1 (HMGB1 ) protein is secreted by activated cells of the innate immune system and/or released by injured tissues and necrotic cells; HMGB1 up-regulates proinflammatory cytokines in several inflammatory diseases.22178603 2012
×
Entrez Id: 1508
Gene Symbol: CTSB
CTSB
Necrosis
0.300
Biomarker
CTD_human
The regulation of cysteine cathepsins and cystatins in human gliomas.
22287159 2012
×
Entrez Id: 351
Gene Symbol: APP
APP
Necrosis
0.300
Biomarker
CTD_human
Protective effects of ω-conotoxin on amyloid-β-induced damage in PC12 cells.
21839817 2011
×
Entrez Id: 10533
Gene Symbol: ATG7
ATG7
Necrosis
0.300
Therapeutic
CTD_human
Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.
21081844 2011