×
Entrez Id: 596
Gene Symbol: BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
"Xiusanzhen" can regulate the expression of hippocampal Bcl-2 and Bax proteins in AD rats, which may contribute to its clinical effect in relieving AD , and the therapeutic effect depends on the integrity of the olfactory nerve pathway.
21585051 2011
×
Entrez Id: 581
Gene Symbol: BAX
BAX
Alzheimer's Disease
0.520
Therapeutic
RGD
"Xiusanzhen" can regulate the expression of hippocampal Bcl-2 and Bax proteins in AD rats, which may contribute to its clinical effect in relieving AD , and the therapeutic effect depends on the integrity of the olfactory nerve pathway.
21585051 2011
×
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
Alzheimer's Disease
0.700
Therapeutic
RGD
A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model.
28342971 2017
×
Entrez Id: 3551
Gene Symbol: IKBKB
IKBKB
Alzheimer's Disease
0.220
Therapeutic
RGD
Acetylpuerarin reduces inflammation and improves memory function in a rat model of Alzheimer's disease induced by Abeta1-42.
24380241 2013
×
Entrez Id: 102
Gene Symbol: ADAM10
ADAM10
Alzheimer's Disease
0.700
Biomarker
RGD
Acrolein induces Alzheimer's disease-like pathologies in vitro and in vivo.
23296102 2013
×
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
Alzheimer's Disease
0.300
Therapeutic
RGD
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils.
12610652 2003
×
Entrez Id: 4311
Gene Symbol: MME
MME
Alzheimer's Disease
0.300
Therapeutic
RGD
After 28-day administration of NEK and piracetam, the abilities of learning and memory of AD rats in piracetam and low-dose, medium-dose and high-dose NEK groups were significantly improved as compared with the untreated group (P<0.01 or P<0.05); the expression of Abeta(1-42) in hippocampal tissues was decreased (P<0.01 or P<0.05) and the expression of NEP was increased (P<0.01 or P<0.05), especially in the high-dose NEK group.
20141738 2010
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Alzheimer's Disease
0.600
Biomarker
RGD
Akebia Saponin D attenuates amyloid β-induced cognitive deficits and inflammatory response in rats: involvement of Akt/NF-κB pathway.
22963993 2012
×
Entrez Id: 3952
Gene Symbol: LEP
LEP
Alzheimer's Disease
0.600
Therapeutic
RGD
Amyloid beta lowering and cognition enhancing effects of ghrelin receptor analog [D-Lys (3)] GHRP-6 in rat model of obesity.
25296496 2014
×
Entrez Id: 4133
Gene Symbol: MAP2
MAP2
Alzheimer's Disease
0.300
Biomarker
RGD
An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide.
22083255 2012
×
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
Alzheimer's Disease
0.700
Therapeutic
RGD
Antioxidative and Neuroprotective Effects of Curcumin in an Alzheimer's Disease Rat Model Co-Treated with Intracerebroventricular Streptozotocin and Subcutaneous D-Galactose.
27060945 2016
×
Entrez Id: 596
Gene Symbol: BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model.
29587274 2018
×
Entrez Id: 836
Gene Symbol: CASP3
CASP3
Alzheimer's Disease
0.600
Therapeutic
RGD
Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model.
29587274 2018
×
Entrez Id: 581
Gene Symbol: BAX
BAX
Alzheimer's Disease
0.520
Therapeutic
RGD
Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model.
29587274 2018
×
Entrez Id: 599
Gene Symbol: BCL2L2
BCL2L2
Alzheimer's Disease
0.210
Therapeutic
RGD
Beta-asarone improves cognitive function by suppressing neuronal apoptosis in the beta-amyloid hippocampus injection rats.
20460763 2010
×
Entrez Id: 4803
Gene Symbol: NGF
NGF
Alzheimer's Disease
0.300
Biomarker
RGD
Brain and serum levels of nerve growth factor in a rat model of Alzheimer's disease .
21368378 2011
×
Entrez Id: 3630
Gene Symbol: INS
INS
Alzheimer's Disease
0.530
Biomarker
RGD
Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein.
17448147 2007
INS-IGF2
Alzheimer's Disease
0.210
Biomarker
RGD
Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein.
17448147 2007
×
Entrez Id: 836
Gene Symbol: CASP3
CASP3
Alzheimer's Disease
0.600
Therapeutic
RGD
CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease.
29777699 2018
×
Entrez Id: 596
Gene Symbol: BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease.
29777699 2018
×
Entrez Id: 581
Gene Symbol: BAX
BAX
Alzheimer's Disease
0.520
Therapeutic
RGD
CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease.
29777699 2018
×
Entrez Id: 842
Gene Symbol: CASP9
CASP9
Alzheimer's Disease
0.210
Therapeutic
RGD
CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease.
29777699 2018
×
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
Alzheimer's Disease
0.700
Biomarker
RGD
Central angiotensin II-induced Alzheimer-like tau phosphorylation in normal rat brains.
22982863 2012
×
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
Alzheimer's Disease
0.300
Biomarker
RGD
Changes in copper metabolism in different compartments of the brain in rats with induced fibrillogenesis.
20027333 2009
×
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
Alzheimer's Disease
0.210
Biomarker
RGD
Changes in copper metabolism in different compartments of the brain in rats with induced fibrillogenesis.
20027333 2009