×
Entrez Id: 7498
Gene Symbol: XDH
XDH
Kidney Failure, Chronic
0.200
Therapeutic
RGD
Nicorandil, a K(atp) channel opener, alleviates chronic renal injury by targeting podocytes and macrophages.
22622455 2012
×
Entrez Id: 7412
Gene Symbol: VCAM1
VCAM1
Kidney Failure, Chronic
0.200
Biomarker
RGD
High-calorie diet with moderate protein restriction prevents cachexia and ameliorates oxidative stress, inflammation and proteinuria in experimental chronic kidney disease.
20820841 2010
×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
Kidney Failure, Chronic
0.600
Biomarker
RGD
Only animals from the 1WIK group developed severe chronic renal failure , glomerulosclerosis, interstitial fibrosis, and upregulation of transforming growth factor-beta(1 ) (TGF-beta(1 )) gene, which was associated with increased TGF-beta(1 ) protein expression in tubular epithelial cells, arterioles, and in areas of mononuclear interstitial cell infiltrate.
10919844 2000
×
Entrez Id: 7015
Gene Symbol: TERT
TERT
Kidney Failure, Chronic
0.200
Therapeutic
RGD
Angiogenic effect of endothelial progenitor cells transfected with telomerase reverse transcriptase on peritubular microvessel in five out of six subtotal nephrectomy rats.
23013219 2012
×
Entrez Id: 6721
Gene Symbol: SREBF2
SREBF2
Kidney Failure, Chronic
0.500
Biomarker
RGD
Despite increased SREBP-2 gene expression we found LDL-receptor mRNA level to be lower than in controls, suggesting SREBP-2 independent mechanisms of LDL-receptor transcriptional regulation in CRF rats.
16814791 2007
×
Entrez Id: 8435
Gene Symbol: SOAT2
SOAT2
Kidney Failure, Chronic
0.200
Biomarker
RGD
The CRF animals showed a significant reduction in creatinine clearance, marked hypertriglyceridemia, modest hypercholesterolemia, and significant upregulation of hepatic tissue ACAT-2 protein and mRNA abundance.
12217884 2002
×
Entrez Id: 113235
Gene Symbol: SLC46A1
SLC46A1
Kidney Failure, Chronic
0.200
Biomarker
RGD
Effect of chronic kidney disease on the expression of thiamin and folic acid transporters.
21149507 2011
×
Entrez Id: 6569
Gene Symbol: SLC34A1
SLC34A1
Kidney Failure, Chronic
0.300
Biomarker
RGD
The pathophysiology of early-stage chronic kidney disease-mineral bone disorder (CKD-MBD) and response to phosphate binders in the rat.
21826734 2011
×
Entrez Id: 6569
Gene Symbol: SLC34A1
SLC34A1
Kidney Failure, Chronic
0.300
Biomarker
RGD
Regulation of NaPi-IIa mRNA and transporter protein in chronic renal failure: role of parathyroid hormone (PTH) and dietary phosphate (Pi).
15452708 2004
×
Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
Kidney Failure, Chronic
0.300
Biomarker
RGD
Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy.
12110012 2002
×
Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
Kidney Failure, Chronic
0.300
Biomarker
RGD
Protein and mRNA expression levels of Oat1, Oat 3, Oct1, and Oct2 were significantly decreased in adenine-induced CRF rats.
23280877 2013
×
Entrez Id: 80704
Gene Symbol: SLC19A3
SLC19A3
Kidney Failure, Chronic
0.210
Biomarker
RGD
Effect of chronic kidney disease on the expression of thiamin and folic acid transporters.
21149507 2011
×
Entrez Id: 10560
Gene Symbol: SLC19A2
SLC19A2
Kidney Failure, Chronic
0.200
Biomarker
RGD
Effect of chronic kidney disease on the expression of thiamin and folic acid transporters.
21149507 2011
×
Entrez Id: 6573
Gene Symbol: SLC19A1
SLC19A1
Kidney Failure, Chronic
0.200
Biomarker
RGD
Effect of chronic kidney disease on the expression of thiamin and folic acid transporters.
21149507 2011
×
Entrez Id: 6469
Gene Symbol: SHH
SHH
Kidney Failure, Chronic
0.200
Biomarker
RGD
Sonic hedgehog is a novel tubule-derived growth factor for interstitial fibroblasts after kidney injury.
24744439 2014
SERPINE1
Kidney Failure, Chronic
0.510
Therapeutic
RGD
An integrated lipidomics and metabolomics reveal nephroprotective effect and biochemical mechanism of Rheum officinale in chronic renal failure.
26903149 2016
×
Entrez Id: 55328
Gene Symbol: RNLS
RNLS
Kidney Failure, Chronic
0.210
Biomarker
RGD
Catecholamines regulate the activity, secretion, and synthesis of renalase.
18299506 2008
×
Entrez Id: 5970
Gene Symbol: RELA
RELA
Kidney Failure, Chronic
0.510
Biomarker
RGD
Melatonin ameliorates oxidative stress, inflammation, proteinuria, and progression of renal damage in rats with renal mass reduction.
18077597 2008
×
Entrez Id: 5741
Gene Symbol: PTH
PTH
Kidney Failure, Chronic
0.300
Biomarker
RGD
Two novel vitamin D receptor modulators with similar structures exhibit different hypercalcemic effects in 5/6 nephrectomized uremic rats.
23548814 2013
×
Entrez Id: 5741
Gene Symbol: PTH
PTH
Kidney Failure, Chronic
0.300
Biomarker
RGD
The pathophysiology of early-stage chronic kidney disease-mineral bone disorder (CKD-MBD) and response to phosphate binders in the rat.
21826734 2011
×
Entrez Id: 5741
Gene Symbol: PTH
PTH
Kidney Failure, Chronic
0.300
Biomarker
RGD
Dietary phosphate binding and loading alter kidney angiotensin-converting enzyme mRNA and protein content in 5/6 nephrectomized rats.
22517117 2012
×
Entrez Id: 5734
Gene Symbol: PTGER4
PTGER4
Kidney Failure, Chronic
0.200
Therapeutic
RGD
Thus, agonism of EP2 and EP4 receptors may provide a basis for treating acute and chronic kidney failure .
16871242 2006
×
Entrez Id: 10631
Gene Symbol: POSTN
POSTN
Kidney Failure, Chronic
0.200
Biomarker
RGD
Periostin: novel tissue and urinary biomarker of progressive renal injury induces a coordinated mesenchymal phenotype in tubular cells.
22167593 2012
×
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
Kidney Failure, Chronic
0.210
Biomarker
RGD
[Curative machanism of Shenle capsule on 5/6 nephrectomy rats].
15506291 2004
×
Entrez Id: 5228
Gene Symbol: PGF
PGF
Kidney Failure, Chronic
0.200
Biomarker
RGD
Microvasculature change and placenta growth factor expression in the early stage of a rat remnant kidney model.
16543713 2006