Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3565
Gene Symbol: IL4
IL4
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke. 23028794

2012

Entrez Id: 942
Gene Symbol: CD86
CD86
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke. 19053043

2009

Entrez Id: 8655
Gene Symbol: DYNLL1
DYNLL1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Induction of protein inhibitor of neuronal nitric oxide synthase/cytoplasmic dynein light chain following cerebral ischemia. 9522364

1998

Entrez Id: 142
Gene Symbol: PARP1
PARP1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke. 25882840

2015

Entrez Id: 1961
Gene Symbol: EGR4
EGR4
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke. 22645329

2012

Entrez Id: 9131
Gene Symbol: AIFM1
AIFM1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Bcl-2 transfection via herpes simplex virus blocks apoptosis-inducing factor translocation after focal ischemia in the rat. 15181376

2004

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke. 23028794

2012

Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke. 17473852

2008

Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Hesperidin ameliorates functional and histological outcome and reduces neuroinflammation in experimental stroke. 21959178

2011

Entrez Id: 84329
Gene Symbol: HVCN1
HVCN1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Neurovascular protection in voltage-gated proton channel Hv1 knock-out rats after ischemic stroke: interaction with Na 31250553

2019

Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Activation of cerebral peroxisome proliferator-activated receptors γ (PPARγ) reduces neuronal damage in the substantia nigra after transient focal cerebral ischaemia in the rat. 21366664

2011

Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD HDAC4/5-HMGB1 signalling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury. 23480850

2013

Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD 4-hydroxybenzyl alcohol ameliorates cerebral injury in rats by antioxidant action. 21120604

2011

Entrez Id: 163
Gene Symbol: AP2B1
AP2B1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration. 19240038

2009

Entrez Id: 2597
Gene Symbol: GAPDH
GAPDH
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke. 25882840

2015

Entrez Id: 63827
Gene Symbol: BCAN
BCAN
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortex. 15869933

2005

Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Temporal profile of tissue plasminogen activator (tPA) and inhibitor expression after transient focal cerebral ischemia. 14512838

2003

Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Transcriptomics of post-stroke angiogenesis in the aged brain. 24672479

2014

Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Expression of interleukin-9 and its upstream stimulating factors in rats with ischemic stroke. 25652434

2015

Entrez Id: 5803
Gene Symbol: PTPRZ1
PTPRZ1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortex. 15869933

2005

Entrez Id: 2693
Gene Symbol: GHSR
GHSR
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Neuroprotective effect of ghrelin is associated with decreased expression of prostate apoptosis response-4. 19352052

2009

Entrez Id: 3567
Gene Symbol: IL5
IL5
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke. 23028794

2012

Entrez Id: 2074
Gene Symbol: ERCC6
ERCC6
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Effect of dextromethorphan, a NMDA antagonist, on DNA repair in rat photochemical thrombotic cerebral ischemia. 9974119

1999

Entrez Id: 177
Gene Symbol: AGER
AGER
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Neamine induces neuroprotection after acute ischemic stroke in type one diabetic rats. 24211797

2014

Entrez Id: 2475
Gene Symbol: MTOR
MTOR
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD PRAS40 plays a pivotal role in protecting against stroke by linking the Akt and mTOR pathways. 24583056

2014