Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Therapeutic RGD A high-potassium diet reduces infarct size and improves vascular structure in hypertensive rats. 16917016

2007

Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Therapeutic RGD A high-potassium diet reduces infarct size and improves vascular structure in hypertensive rats. 16917016

2007

Entrez Id: 4968
Gene Symbol: OGG1
OGG1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Therapeutic RGD Ebselen attenuates oxidative DNA damage and enhances its repair activity in the thalamus after focal cortical infarction in hypertensive rats. 17920569

2007

Entrez Id: 664
Gene Symbol: BNIP3
BNIP3
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD BNIP3 upregulation and EndoG translocation in delayed neuronal death in stroke and in hypoxia. 17379825

2007

Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke. 17473852

2008

Entrez Id: 7378
Gene Symbol: UPP1
UPP1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Uridine protects cortical neurons from glucose deprivation-induced death: possible role of uridine phosphorylase. 18457515

2008

Entrez Id: 5074
Gene Symbol: PAWR
PAWR
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Neuroprotective effect of ghrelin is associated with decreased expression of prostate apoptosis response-4. 19352052

2009

Entrez Id: 29924
Gene Symbol: EPN1
EPN1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration. 19240038

2009

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Enriched environment reduces apolipoprotein E (ApoE) in reactive astrocytes and attenuates inflammation of the peri-infarct tissue after experimental stroke. 19623195

2009

Entrez Id: 9892
Gene Symbol: SNAP91
SNAP91
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration. 19240038

2009

Entrez Id: 942
Gene Symbol: CD86
CD86
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke. 19053043

2009

Entrez Id: 163
Gene Symbol: AP2B1
AP2B1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration. 19240038

2009

Entrez Id: 2693
Gene Symbol: GHSR
GHSR
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Neuroprotective effect of ghrelin is associated with decreased expression of prostate apoptosis response-4. 19352052

2009

Entrez Id: 51738
Gene Symbol: GHRL
GHRL
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Therapeutic RGD Neuroprotective effect of ghrelin is associated with decreased expression of prostate apoptosis response-4. 19352052

2009

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Therapeutic RGD The neuroprotective effects of Tanshinone IIA are associated with induced nuclear translocation of TORC1 and upregulated expression of TORC1, pCREB and BDNF in the acute stage of ischemic stroke. 20417695

2010

Entrez Id: 1965
Gene Symbol: EIF2S1
EIF2S1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Therapeutic RGD Endoplasmic reticulum stress plays critical role in brain damage after cerebral ischemia/reperfusion in rats. 19763736

2010

Entrez Id: 361
Gene Symbol: AQP4
AQP4
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Therapeutic RGD Beneficial effect of agmatine on brain apoptosis, astrogliosis, and edema after rat transient cerebral ischemia. 20815926

2010

Entrez Id: 23373
Gene Symbol: CRTC1
CRTC1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Therapeutic RGD The neuroprotective effects of Tanshinone IIA are associated with induced nuclear translocation of TORC1 and upregulated expression of TORC1, pCREB and BDNF in the acute stage of ischemic stroke. 20417695

2010

Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.500 Biomarker RGD Proteomic analysis of rat plasma following transient focal cerebral ischemia. 22103620

2011

Entrez Id: 8883
Gene Symbol: NAE1
NAE1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Focal transient ischemia increases APP-BP1 expression in neural progenitor cells. 21386696

2011

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Proteomic analysis of rat plasma following transient focal cerebral ischemia. 22103620

2011

Entrez Id: 665
Gene Symbol: BNIP3L
BNIP3L
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Selective inhibition of early--but not late--expressed HIF-1α is neuroprotective in rats after focal ischemic brain damage. 21029239

2011

Entrez Id: 1392
Gene Symbol: CRH
CRH
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD The function of the adrenocortical axis in permanent middle cerebral artery occlusion: effect of glucocorticoids on the neurological outcome. 21741032

2011

Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Hepcidin is involved in iron regulation in the ischemic brain. 21957487

2011

Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Hesperidin ameliorates functional and histological outcome and reduces neuroinflammation in experimental stroke. 21959178

2011