Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4086
Gene Symbol: SMAD1
SMAD1
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Biomarker RGD Chinese herbal formula Qilong-Lishui granule improves puromycin aminonucleoside-induced renal injury through regulation of bone morphogenetic proteins. 17803470

2007
Entrez Id: 6337
Gene Symbol: SCNN1A
SCNN1A
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Biomarker RGD Increased expression and apical targeting of renal ENaC subunits in puromycin aminonucleoside-induced nephrotic syndrome in rats. 15075188

2004
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Therapeutic RGD Cyclosporine A protects podocytes via stabilization of cofilin-1 expression in the unphosphorylated state. 24737737

2014
Entrez Id: 1644
Gene Symbol: DDC
DDC
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Biomarker RGD Blunted renal dopaminergic system activity in puromycin aminonucleoside-induced nephrotic syndrome. 16204272

2006
Entrez Id: 3565
Gene Symbol: IL4
IL4
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Therapeutic RGD Protection Effect of Zhen-Wu-Tang on Adriamycin-Induced Nephrotic Syndrome via Inhibiting Oxidative Lesions and Inflammation Damage. 24812565

2014
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Biomarker RGD Disorder of fatty acid metabolism in the kidney of PAN-induced nephrotic rats. 22874759

2012
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Biomarker RGD The NS group showed marked proteinuria, hypoalbuminemia, decreased fractional excretion of Na (FENa), reduced urinary NOx excretion, and severe reduction of iNOS and nNOS protein abundance in the kidney. 12853118

2003
Entrez Id: 6338
Gene Symbol: SCNN1B
SCNN1B
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Biomarker RGD Increased expression and apical targeting of renal ENaC subunits in puromycin aminonucleoside-induced nephrotic syndrome in rats. 15075188

2004
Entrez Id: 38
Gene Symbol: ACAT1
ACAT1
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Biomarker RGD Sterol regulatory element-binding proteins, liver X receptor, ABCA1 transporter, CD36, scavenger receptors A1 and B1 in nephrotic kidney. 19147991

2009
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Biomarker RGD Changes in glycerophospholipid profile in experimental nephrotic syndrome. 8692015

1996
Entrez Id: 8694
Gene Symbol: DGAT1
DGAT1
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Biomarker RGD Nephrotic syndrome results in up-regulation of hepatic DGAT-1 expression and activity, which can potentially contribute to the associated hypertriglyceridemia by enhancing triglyceride synthesis. 15200432

2004
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Biomarker RGD Down-regulation of hepatic lipase expression in experimental nephrotic syndrome. 9186885

1997