Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		nuclear receptor subfamily 1 group H member 3 0.566 0.692 0.90
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2007 2007
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		glutathione S-transferase theta 1 0.393 0.923 1.5E-04
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 3 0 2008 2014
Entrez Id: 213
Gene Symbol: ALB
ALB 		albumin 0.317 0.962 0.64
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2008 2012
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2 		ATP binding cassette subfamily C member 2 0.483 0.808 5.2E-47
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2008 2008
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2008 2009
Entrez Id: 5428
Gene Symbol: POLG
POLG 		DNA polymerase gamma, catalytic subunit 0.457 0.846 2.1E-09
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 2 0 2008 2014
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		heme oxygenase 1 0.381 0.923 9.7E-03
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 2 0 2008 2013
Entrez Id: 581
Gene Symbol: BAX
BAX 		BCL2 associated X, apoptosis regulator 0.417 0.885 0.32
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2008 2008
Entrez Id: 4217
Gene Symbol: MAP3K5
MAP3K5 		mitogen-activated protein kinase kinase kinase 5 0.513 0.808 0.52
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2008 2008
Entrez Id: 259
Gene Symbol: AMBP
AMBP 		alpha-1-microglobulin/bikunin precursor 0.537 0.731 2.8E-13
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2008 2008
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1 		ATP binding cassette subfamily C member 1 0.445 0.808 1.2E-03
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2008 2008
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		interleukin 1 beta 0.276 0.962 0.13
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 2 0 2009 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		interleukin 17A 0.324 0.923 4.3E-02
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2009 2014
Entrez Id: 3606
Gene Symbol: IL18
IL18 		interleukin 18 0.365 0.923 3.1E-02
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		major histocompatibility complex, class I, B 0.379 0.885 3.9E-05
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 3875
Gene Symbol: KRT18
KRT18 		keratin 18 0.530 0.692 0.73
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 1719
Gene Symbol: DHFR
DHFR 		dihydrofolate reductase 0.513 0.808 3.4E-02
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		catenin beta 1 0.303 0.885 1.00
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		high mobility group box 1 0.368 0.923 0.82
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 6888
Gene Symbol: TALDO1
TALDO1 		transaldolase 1 0.608 0.654 2.5E-06
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 3827
Gene Symbol: KNG1
KNG1 		kininogen 1 0.481 0.885 3.2E-10
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2010 2019
Entrez Id: 3934
Gene Symbol: LCN2
LCN2 		lipocalin 2 0.405 0.885 1.1E-09
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2010 2011
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2 		nuclear receptor subfamily 1 group I member 2 0.418 0.846 7.3E-09
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2010 2017
Entrez Id: 1131
Gene Symbol: CHRM3
CHRM3 		cholinergic receptor muscarinic 3 0.464 0.885 0.99
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2010 2010
Entrez Id: 405
Gene Symbol: ARNT
ARNT 		aryl hydrocarbon receptor nuclear translocator 0.575 0.692 1.00
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2010 2010