| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 1.000 | 12 | 0 | 1998 | 2019 | ||||||||
|
interferon regulatory factor 5 | 0.489 | 0.731 | 9.0E-03 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 2007 | 2019 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 2004 | 2018 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 2009 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.080 | None | 0.875 | 8 | 0 | 1991 | 2019 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2002 | 2020 | ||||||||
|
interferon gamma | 0.288 | 0.962 | 0.47 |
|
disease | 0.060 | None | 1.000 | 6 | 3 | 1994 | 2018 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.060 | None | 0.833 | 6 | 0 | 1996 | 2010 | ||||||||
|
interleukin 18 | 0.365 | 0.923 | 3.1E-02 |
|
disease | 0.050 | None | 0.800 | 5 | 1 | 2002 | 2019 | ||||||||
|
TNF superfamily member 13b | 0.460 | 0.731 | 0.98 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2010 | 2019 | ||||||||
|
interleukin 2 | 0.336 | 0.885 | 0.48 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2002 | 2019 | ||||||||
|
protein tyrosine phosphatase non-receptor type 22 | 0.438 | 0.846 | 3.5E-21 |
|
disease | 0.050 | None | 1.000 | 5 | 1 | 2004 | 2016 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2008 | 2019 | ||||||||
|
CD247 molecule | 0.539 | 0.731 | 1.7E-02 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2005 | 2017 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2002 | 2006 | ||||||||
|
toll like receptor 9 | 0.411 | 0.885 | 9.8E-06 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2015 | 2019 | ||||||||
|
CD40 ligand | 0.414 | 0.846 | 0.72 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1999 | 2017 | ||||||||
|
complement C3 | 0.445 | 0.885 | 0.90 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 1988 | 2017 | ||||||||
|
tyrosine kinase 2 | 0.505 | 0.769 | 4.5E-08 |
|
disease | 0.040 | None | 1.000 | 4 | 5 | 2007 | 2019 | ||||||||
|
BLK proto-oncogene, Src family tyrosine kinase | 0.585 | 0.769 | 8.3E-14 |
|
disease | 0.030 | None | 1.000 | 3 | 1 | 2009 | 2017 | ||||||||
|
TNF superfamily member 4 | 0.540 | 0.808 | 4.9E-02 |
|
disease | 0.030 | None | 1.000 | 3 | 1 | 2013 | 2018 | ||||||||
|
interleukin 2 receptor subunit alpha | 0.389 | 0.885 | 5.5E-02 |
|
disease | 0.030 | None | 0.667 | 3 | 0 | 2009 | 2011 | ||||||||
|
toll like receptor 2 | 0.361 | 0.923 | 1.0E-06 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2015 | 2016 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.030 | None | 0.667 | 3 | 0 | 2016 | 2019 | ||||||||
|
leptin | 0.349 | 0.846 | 0.46 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2015 | 2020 |