Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
CUI: C0014060
Disease: Encephalitis, St. Louis
Encephalitis, St. Louis 		0.100 Biomarker BEFREE Coordination between innate immune cells, type I IFNs and IRF5 drives SLE pathogenesis. 31130331

2019
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
CUI: C0014060
Disease: Encephalitis, St. Louis
Encephalitis, St. Louis 		0.100 Biomarker BEFREE Genetic Versus Non-genetic Drivers of SLE: Implications of IRF5 Dysregulation in Both Roads Leading to SLE. 30645688

2019
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
CUI: C0014060
Disease: Encephalitis, St. Louis
Encephalitis, St. Louis 		0.100 Biomarker BEFREE IRF5 is elevated in childhood-onset SLE and regulated by histone acetyltransferase and histone deacetylase inhibitors. 28525378

2017
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
CUI: C0014060
Disease: Encephalitis, St. Louis
Encephalitis, St. Louis 		0.100 AlteredExpression BEFREE RNA-Seq for enrichment and analysis of IRF5 transcript expression in SLE. 23349905

2013
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
CUI: C0014060
Disease: Encephalitis, St. Louis
Encephalitis, St. Louis 		0.100 Biomarker BEFREE SLE serum was identified as a trigger for IRF-5 nuclear accumulation; however, neither IFNα nor SLE immune complexes could induce nuclear localization. 21968701

2012
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
CUI: C0014060
Disease: Encephalitis, St. Louis
Encephalitis, St. Louis 		0.100 GeneticVariation BEFREE SLE-associated IRF5 haplotypes were correlated with the expression data and with the best cis-regulatory models. 21627826

2011
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
CUI: C0014060
Disease: Encephalitis, St. Louis
Encephalitis, St. Louis 		0.100 AlteredExpression BEFREE Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus. 20479222

2010
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
CUI: C0014060
Disease: Encephalitis, St. Louis
Encephalitis, St. Louis 		0.100 Biomarker BEFREE The significantly higher frequency of homozygote individuals for the risk haplotype among Mexican SLE patients could be the result of genetic admixture, and suggests the possibility that IRF5 could be involved in the more active disease and organ involvement known to occur among Mexican SLE patients. 17476532

2007
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
CUI: C0014060
Disease: Encephalitis, St. Louis
Encephalitis, St. Louis 		0.100 Biomarker BEFREE Opposed independent effects and epistasis in the complex association of IRF5 to SLE. 17568788

2007
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
CUI: C0014060
Disease: Encephalitis, St. Louis
Encephalitis, St. Louis 		0.100 Biomarker BEFREE Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation. 17189288

2007