Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 215
Gene Symbol: ABCD1
ABCD1
ATP binding cassette subfamily D member 1 0.563 0.731 1.00
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 1.000 definitive 0.977 266 89 1981 2020
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.320 None 1.000 3 0 2005 2018
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.320 None 1.000 3 1 2005 2016
Entrez Id: 5189
Gene Symbol: PEX1
PEX1
peroxisomal biogenesis factor 1 0.538 0.769 1.1E-14
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.300 moderate 1.000 1 0 2005 2005
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
heme oxygenase 1 0.381 0.923 9.7E-03
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.300 None 1.000 1 0 2005 2005
Entrez Id: 55670
Gene Symbol: PEX26
PEX26
peroxisomal biogenesis factor 26 0.584 0.615 0.93
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.300 None 1.000 1 0 2003 2003
Entrez Id: 5194
Gene Symbol: PEX13
PEX13
peroxisomal biogenesis factor 13 0.597 0.654 5.9E-05
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.300 None 1.000 1 0 1999 1999
Entrez Id: 225
Gene Symbol: ABCD2
ABCD2
ATP binding cassette subfamily D member 2 0.711 0.500 4.7E-06
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.100 None 1.000 29 0 1997 2019
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
cytochrome P450 family 2 subfamily E member 1 0.459 0.885 8.1E-09
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.100 None 0.933 15 0 1995 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.100 None 0.929 14 0 1995 2019
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
ATP binding cassette subfamily B member 6 (Langereis blood group) 0.431 0.885 8.6E-19
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.100 None 1.000 10 0 1995 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.090 None 1.000 9 2 2010 2019
Entrez Id: 5825
Gene Symbol: ABCD3
ABCD3
ATP binding cassette subfamily D member 3 0.751 0.423 7.8E-03
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.080 None 1.000 8 0 1998 2014
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3
patatin like phospholipase domain containing 3 0.556 0.692 5.7E-08
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.080 None 1.000 8 1 2011 2018
Entrez Id: 929
Gene Symbol: CD14
CD14
CD14 molecule 0.392 0.885 4.9E-05
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.080 None 0.750 8 0 2001 2018
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
ATP binding cassette subfamily G member 2 (Junior blood group) 0.419 0.885 2.1E-32
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.080 None 1.000 8 0 2003 2018
Entrez Id: 81693
Gene Symbol: AMN
AMN
amnion associated transmembrane protein 0.678 0.577 2.7E-04
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.080 None 1.000 8 0 1981 2019
Entrez Id: 23205
Gene Symbol: ACSBG1
ACSBG1
acyl-CoA synthetase bubblegum family member 1 0.603 0.654 4.0E-05
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.070 None 1.000 7 0 2000 2016
Entrez Id: 3586
Gene Symbol: IL10
IL10
interleukin 10 0.281 0.923 5.9E-03
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.070 None 0.714 7 0 2000 2018
Entrez Id: 11001
Gene Symbol: SLC27A2
SLC27A2
solute carrier family 27 member 2 0.700 0.462 6.4E-09
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.070 None 0.857 7 0 1995 2005
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.060 None 0.833 6 0 2005 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.060 None 1.000 6 0 2002 2018
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
hepcidin antimicrobial peptide 0.433 0.846 8.2E-03
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.040 None 1.000 4 0 2007 2017
Entrez Id: 53345
Gene Symbol: TM6SF2
TM6SF2
transmembrane 6 superfamily member 2 0.638 0.462 3.6E-05
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.040 None 1.000 4 1 2015 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
disease 0.040 None 0.750 4 0 2002 2018