Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Prognostic Significance of VEGFC and VEGFR1 mRNA Expression According to HER2 Status in Breast Cancer: A Study of Primary Tumors from Patients with High-risk Early Breast Cancer Participating in a Randomized Hellenic Cooperative Oncology Group Trial. 26124351

2015

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Prognostic Significance of VEGFC and VEGFR1 mRNA Expression According to HER2 Status in Breast Cancer: A Study of Primary Tumors from Patients with High-risk Early Breast Cancer Participating in a Randomized Hellenic Cooperative Oncology Group Trial. 26124351

2015

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Molecular profiling of single circulating tumor cells with diagnostic intention. 25358515

2015

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Molecular profiling of single circulating tumor cells with diagnostic intention. 25358515

2015

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models. 25221644

2014

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models. 25221644

2014

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human In situ detection of HER2:HER2 and HER2:HER3 protein-protein interactions demonstrates prognostic significance in early breast cancer. 21638049

2012

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation. 19617202

2012

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Multiple roles of cyclin-dependent kinase 4/6 inhibitors in cancer therapy. 22302033

2012

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human In situ detection of HER2:HER2 and HER2:HER3 protein-protein interactions demonstrates prognostic significance in early breast cancer. 21638049

2012

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation. 19617202

2012

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Multiple roles of cyclin-dependent kinase 4/6 inhibitors in cancer therapy. 22302033

2012

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Immunophenotypic predictive profiling of BRCA1-associated breast cancer. 20941507

2011

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization. 21501481

2011

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization. 21501481

2011

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Immunophenotypic predictive profiling of BRCA1-associated breast cancer. 20941507

2011

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins. 19801490

2010

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Effect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue. 20332317

2010

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Selective death of human breast cancer cells by lytic immunoliposomes: Correlation with their HER2 expression level. 19896266

2010

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins. 19801490

2010

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Effect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue. 20332317

2010

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model. 20197467

2010

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Selective death of human breast cancer cells by lytic immunoliposomes: Correlation with their HER2 expression level. 19896266

2010

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model. 20197467

2010

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Relevance of breast cancer antiestrogen resistance genes in human breast cancer progression and tamoxifen resistance. 19075277

2009