Source: GWASDB

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
Oligoarticular Juvenile Idiopathic Arthritis
0.100 GeneticVariation GWASDB Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. 23603761

2013

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.100 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.100 GeneticVariation GWASDB Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. 22057235

2011

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0021053
Disease: Immune System Diseases
Immune System Diseases
0.100 GeneticVariation GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967

2011

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases
0.180 GeneticVariation GWASDB Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233

2012

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.200 GeneticVariation GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967

2011

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.430 GeneticVariation GWASDB Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. 22190364

2011

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.450 GeneticVariation GWASDB A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. 24097066

2013

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis
0.470 GeneticVariation GWASDB Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis. 22961000

2012

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis
0.470 GeneticVariation GWASDB Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population. 23000144

2012

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis
0.470 GeneticVariation GWASDB Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants. 22936693

2012

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.500 GeneticVariation GWASDB Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342

2014

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
0.500 GeneticVariation GWASDB A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci. 23740937

2013

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.500 GeneticVariation GWASDB We also found significantly lower mRNA expression of STAT4 in HCC tumor tissues compared with paired adjacent nontumor tissues (P = 2.33 × 10(-14)). 23242368

2013

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.500 GeneticVariation GWASDB Functional variants in NFKBIE and RTKN2 involved in activation of the NF-κB pathway are associated with rheumatoid arthritis in Japanese. 23028356

2012

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.500 GeneticVariation GWASDB Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. 22446963

2012

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.500 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
0.500 GeneticVariation GWASDB Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. 21750679

2011

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
0.500 GeneticVariation GWASDB Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. 21779181

2011

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.500 GeneticVariation GWASDB Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842

2010

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma
0.500 GeneticVariation GWASDB Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. 20383147

2010

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome
0.670 GeneticVariation GWASDB Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. 23291587

2013

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome
0.670 GeneticVariation GWASDB Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study. 23001997

2012

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.700 GeneticVariation GWASDB GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. 24871463

2014

Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.700 GeneticVariation GWASDB Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568

2013