|
rs7574865
|
|
Lupus Erythematosus, Systemic
|
T |
0.900 |
GeneticVariation
|
GWASDB |
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
|
24871463 |
2014 |
|
rs7574865
|
|
Lupus Erythematosus, Systemic
|
T |
0.900 |
GeneticVariation
|
GWASDB |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
|
rs7574865
|
|
Liver carcinoma
|
G |
0.900 |
GeneticVariation
|
GWASDB |
The risk allele G at rs7574865 was significantly associated with lower mRNA levels of STAT4 in both the HCC tissues and nontumor tissues of 155 individuals with HBV-related HCC (P(trend) = 0.0008 and 0.0002, respectively).
|
23242368 |
2013 |
|
rs7574865
|
|
Rheumatoid Arthritis
|
|
0.900 |
GeneticVariation
|
GWASDB |
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.
|
22446963 |
2012 |
|
rs7574865
|
|
Lupus Erythematosus, Systemic
|
T |
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis.
|
23053960 |
2012 |
|
rs7574865
|
|
Rheumatoid Arthritis
|
|
0.900 |
GeneticVariation
|
GWASDB |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
|
rs7574865
|
|
Autoimmune Diseases
|
T |
0.900 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
|
21383967 |
2011 |
|
rs7574865
|
|
Lupus Erythematosus, Systemic
|
T |
0.900 |
GeneticVariation
|
GWASDB |
For example, rs7574865 in STAT4 had an OR for anti-dsDNA + SLE of 1.77 (95% CI 1.57-1.99, p = 2.0E-20) compared to an OR for anti-dsDNA - SLE of 1.26 (95% CI 1.12-1.41, p = 2.4E-04), with p(heterogeneity)<0.0005.
|
21408207 |
2011 |
|
rs7574865
|
|
Rheumatoid Arthritis
|
T |
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
|
20453842 |
2010 |
|
rs7574865
|
|
Lupus Erythematosus, Systemic
|
A |
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.
|
19838193 |
2009 |
|
rs7574865
|
|
Lupus Erythematosus, Systemic
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
|
18204446 |
2008 |
|
rs7574865
|
|
Lupus Erythematosus, Systemic
|
T |
0.900 |
GeneticVariation
|
GWASDB |
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
|
18204098 |
2008 |
|
rs7574865
|
|
Systemic Scleroderma
|
T |
0.870 |
GeneticVariation
|
GWASDB |
Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis.
|
21750679 |
2011 |
|
rs10181656
|
|
Rheumatoid Arthritis
|
|
0.820 |
GeneticVariation
|
GWASDB |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
|
rs3821236
|
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation
|
GWASDB |
Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
|
21408207 |
2011 |
|
rs3821236
|
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation
|
GWASDB |
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.
|
19165918 |
2008 |
|
rs7574070
|
|
Behcet Syndrome
|
A |
0.810 |
GeneticVariation
|
GWASDB |
Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.
|
23291587 |
2013 |
|
rs7574070
|
|
Behcet Syndrome
|
|
0.810 |
GeneticVariation
|
GWASDB |
Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.
|
23001997 |
2012 |
|
rs7574865
|
|
Primary biliary cirrhosis
|
T |
0.810 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.
|
23000144 |
2012 |
|
rs7601754
|
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation
|
GWASDB |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
|
rs10168266
|
|
Sjogren's Syndrome
|
T |
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23.
|
24097066 |
2013 |
|
rs10174238
|
|
Oligoarticular Juvenile Idiopathic Arthritis
|
|
0.800 |
GeneticVariation
|
GWASDB |
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
|
23603761 |
2013 |
|
rs11889341
|
|
Rheumatoid Arthritis
|
T |
0.800 |
GeneticVariation
|
GWASDB |
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
|
24390342 |
2014 |
|
rs13426947
|
|
Rheumatoid Arthritis
|
|
0.800 |
GeneticVariation
|
GWASDB |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
|
rs1517352
|
|
Inflammatory Bowel Diseases
|
C |
0.800 |
GeneticVariation
|
GWASDB |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
|
23128233 |
2012 |