Source: GWASDB

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. 24871463

2014
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568

2013
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis. 23053960

2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. 21408207

2011
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193

2009
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB We also found evidence for association (P < 1 x 10(-5)) at FCGR2A, PTPN22 and STAT4, regions previously associated with SLE and other autoimmune diseases, as well as at > or =9 other loci (P < 2 x 10(-7)). 18204446

2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. 19165918

2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASDB Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. 18204098

2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.670 GeneticVariation GWASDB Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. 23291587

2013
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.670 GeneticVariation GWASDB Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study. 23001997

2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 GeneticVariation GWASDB Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342

2014
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.500 GeneticVariation GWASDB A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci. 23740937

2013
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.500 GeneticVariation GWASDB We also found significantly lower mRNA expression of STAT4 in HCC tumor tissues compared with paired adjacent nontumor tissues (P = 2.33 × 10(-14)). 23242368

2013
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 GeneticVariation GWASDB Functional variants in NFKBIE and RTKN2 involved in activation of the NF-κB pathway are associated with rheumatoid arthritis in Japanese. 23028356

2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 GeneticVariation GWASDB Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. 22446963

2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.500 GeneticVariation GWASDB Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. 21750679

2011
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.500 GeneticVariation GWASDB Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. 21779181

2011
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 GeneticVariation GWASDB Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842

2010
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.500 GeneticVariation GWASDB Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. 20383147

2010
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.470 GeneticVariation GWASDB Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis. 22961000

2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.470 GeneticVariation GWASDB Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population. 23000144

2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.470 GeneticVariation GWASDB Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants. 22936693

2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.450 GeneticVariation GWASDB A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. 24097066

2013
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.430 GeneticVariation GWASDB Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. 22190364

2011