Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Apocynin (but not allopurinol) co-treatment prevented (142+/-3 ACTH, 120+/-4 mm Hg apocynin+ACTH, P'<0.001) and reversed ACTH-induced hypertension (133+/-4 to 118+/-5 mm Hg, P<.05). 16053986

2005
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human We hypothesized that ACTH-induced hypertension in the rat is characterized by increased EPO production. 15110907

2004
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Nitric oxide donation lowers blood pressure in adrenocorticotrophic hormone-induced hypertensive rats. 15554453

2004
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Nitric oxide donation lowers blood pressure in adrenocorticotrophic hormone-induced hypertensive rats. 15554453

2004
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Accordingly we hypothesized that ACTH-induced hypertension would be reversed by BH4 supplementation. 15132301

2004
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human We hypothesized that ACTH-induced hypertension in the rat is characterized by increased EPO production. 15110907

2004
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Accordingly we hypothesized that ACTH-induced hypertension would be reversed by BH4 supplementation. 15132301

2004
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human The anti-oxidant Tempol reverses and partially prevents adrenocorticotrophic hormone-induced hypertension in the rat. 12872045

2003
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Lipopolysaccharide reverses adrenocorticotrophic hormone-induced hypertension in the rat. 12887135

2003
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human The anti-oxidant Tempol reverses and partially prevents adrenocorticotrophic hormone-induced hypertension in the rat. 12872045

2003
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Lipopolysaccharide reverses adrenocorticotrophic hormone-induced hypertension in the rat. 12887135

2003
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Circadian blood pressure variability in adrenocorticotrophin-induced hypertension in the rat. 11518849

2001
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Nitric oxide synthase activity in adrenocorticotrophin-induced hypertension in the rat. 11703388

2001
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Telemetric monitoring of adrenocorticotrophin-induced hypertension in mice. 11560123

2001
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Nitric oxide synthase activity in adrenocorticotrophin-induced hypertension in the rat. 11703388

2001
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Telemetric monitoring of adrenocorticotrophin-induced hypertension in mice. 11560123

2001
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Circadian blood pressure variability in adrenocorticotrophin-induced hypertension in the rat. 11518849

2001
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat. 11193135

2000
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat. 11193135

2000
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Role of nitric oxide in adrenocorticotrophin-induced hypertension: L-arginine effects reversed by N-nitro-L-arginine. 11071304

2000
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Role of nitric oxide in adrenocorticotrophin-induced hypertension: L-arginine effects reversed by N-nitro-L-arginine. 11071304

2000
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Vasopressin V1a receptor antagonism does not reverse adrenocorticotrophin-induced hypertension in the rat. 11071300

2000
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat. 11132610

2000
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Vasopressin V1a receptor antagonism does not reverse adrenocorticotrophin-induced hypertension in the rat. 11071300

2000
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat. 11132610

2000