Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0752347
Disease: Lewy Body Disease
Lewy Body Disease 		0.320 Biomarker CTD_human Brain insulin-like growth factor and neurotrophin resistance in Parkinson's disease and dementia with Lewy bodies: potential role of manganese neurotoxicity. 19276553

2009
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0019337
Disease: Heroin Dependence
Heroin Dependence 		0.320 Biomarker CTD_human Chronic heroin and cocaine abuse is associated with decreased serum concentrations of the nerve growth factor and brain-derived neurotrophic factor. 17715210

2007
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0002768
Disease: Congenital Pain Insensitivity
Congenital Pain Insensitivity 		0.320 GermlineCausalMutation ORPHANET A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception. 14976160

2004
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0699739
Disease: Sensory Neuropathy, Hereditary
Sensory Neuropathy, Hereditary 		0.320 Biomarker CTD_human

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0345967
Disease: Malignant mesothelioma
Malignant mesothelioma 		0.310 Biomarker CTD_human A specific pattern of cytokines were found highly expressed in Asb-workers: IFN-alpha (p<0.05), EOTAXIN (p<0.01), RANTES (p<0.001), and in MM patients: IL-12(p40), IL-3, IL-1 alpha, MCP-3, beta-NGF, TNF-beta, RANTES (p<0.001). 25162674

2014
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0010043
Disease: Corneal Ulcer
Corneal Ulcer 		0.310 Therapeutic CTD_human Considering that nerve growth factor exerts beneficial effects in the treatment of major central and peripheral neurodegenerative diseases, skin and corneal ulcers, we asked whether nerve growth factor could also exert a role in Cyclosporine A-induced graft nephrotoxicity. 24244623

2013
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis 		0.310 Biomarker CTD_human Nerve growth factor serum concentrations increase during many inflammatory and autoimmune diseases, glomerulonephritis, chronic kidney disease, end-stage renal disease and, particularly, in renal transplant. 24244623

2013
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.310 Biomarker CTD_human Nerve growth factor serum concentrations increase during many inflammatory and autoimmune diseases, glomerulonephritis, chronic kidney disease, end-stage renal disease and, particularly, in renal transplant. 24244623

2013
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0236663
Disease: Alcohol withdrawal syndrome
Alcohol withdrawal syndrome 		0.310 Biomarker PSYGENET Epigenetic down regulation of nerve growth factor during alcohol withdrawal. 21392176

2013
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0002622
Disease: Amnesia
Amnesia 		0.310 Therapeutic CTD_human Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles. 19694610

2009
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0002622
Disease: Amnesia
Amnesia 		0.310 Therapeutic CTD_human The antiamnesic activity of nerve growth factor (NGF) in various medicinal forms [aqueous NGF solution with and without polysorbate-80 (PS-80) additives, NGF adsorbed on poly(butyl) cyanoacrylate (PBCA) nanoparticles with and without PS-80 coating] has been studied in rats with model amnesia induced by scopolamine (2 mg/kg, s.c.). 16405025

2006
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0037299
Disease: Skin Ulcer
Skin Ulcer 		0.300 Therapeutic CTD_human Exposure to nerve growth factor worsens nephrotoxic effect induced by Cyclosporine A in HK-2 cells. 24244623

2013
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0270715
Disease: Degenerative Diseases, Central Nervous System
Degenerative Diseases, Central Nervous System 		0.300 Therapeutic CTD_human Exposure to nerve growth factor worsens nephrotoxic effect induced by Cyclosporine A in HK-2 cells. 24244623

2013
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0403447
Disease: Chronic Kidney Insufficiency
Chronic Kidney Insufficiency 		0.300 Biomarker CTD_human Exposure to nerve growth factor worsens nephrotoxic effect induced by Cyclosporine A in HK-2 cells. 24244623

2013
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0751733
Disease: Degenerative Diseases, Spinal Cord
Degenerative Diseases, Spinal Cord 		0.300 Therapeutic CTD_human Exposure to nerve growth factor worsens nephrotoxic effect induced by Cyclosporine A in HK-2 cells. 24244623

2013
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.300 Biomarker CTD_human Nerve growth factor serum concentrations increase during many inflammatory and autoimmune diseases, glomerulonephritis, chronic kidney disease, end-stage renal disease and, particularly, in renal transplant. 24244623

2013
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C1704377
Disease: Bright Disease
Bright Disease 		0.300 Biomarker CTD_human Exposure to nerve growth factor worsens nephrotoxic effect induced by Cyclosporine A in HK-2 cells. 24244623

2013
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.300 Therapeutic CTD_human Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice. 22666365

2012
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0085129
Disease: Bronchial Hyperreactivity
Bronchial Hyperreactivity 		0.300 Biomarker CTD_human Blockage of nerve growth factor modulates T cell responses and inhibits allergic inflammation in a mouse model of asthma. 22871964

2012
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0525041
Disease: Neurobehavioral Manifestations
Neurobehavioral Manifestations 		0.300 Therapeutic CTD_human "Intranasal ""painless"" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice." 22666365

2012
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0600467
Disease: Neurogenic Inflammation
Neurogenic Inflammation 		0.300 Biomarker CTD_human Increases in innervation of sensory C-fibers and tachykinin receptors, which mainly involve overproduction of neurotrophins such as nerve growth factor (NGF), may enhance neurogenic inflammation. 21570423

2011
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0273115
Disease: Lung Injury
Lung Injury 		0.300 Therapeutic CTD_human Nerve growth factor enhances Clara cell proliferation after lung injury. 20075049

2010
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0458247
Disease: Allodynia
Allodynia 		0.300 Biomarker CTD_human Hyperalgesic priming is restricted to isolectin B4-positive nociceptors. 20457222

2010
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0751211
Disease: Hyperalgesia, Primary
Hyperalgesia, Primary 		0.300 Biomarker CTD_human Hyperalgesic priming is restricted to isolectin B4-positive nociceptors. 20457222

2010
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0751212
Disease: Hyperalgesia, Secondary
Hyperalgesia, Secondary 		0.300 Biomarker CTD_human Hyperalgesic priming is restricted to isolectin B4-positive nociceptors. 20457222

2010