×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
Malignant neoplasm of ovary
0.900
GeneticVariation
UNIPROT
Both nuclear and cytoplasmic beta-catenin expressions were demonstrated in 4 of the 27 ovarian carcinomas for which tissue samples were available for examination.
10391090
1999
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of ovary
0.800
GeneticVariation
UNIPROT
We identified the BRCA1 /2 genetic mutation test results of 1223 breast cancer patients and 174 patients with ovarian cancer .
28364669
2017
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of ovary
0.800
GeneticVariation
UNIPROT
Four additional missense variants (one in BRCA1 and three in BRCA2) with a possible association with an increased risk ovarian cancer were revealed, resulting in a total frequency of BRCA gene alterations of 17/161 (11%).
14746861
2004
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of ovary
0.800
GeneticVariation
UNIPROT
One hundred and seven ovarian cancer cases were analyzed for BRCA1 alterations using the RNase mismatch cleavage assay followed by direct sequencing.
10196379
1999
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of ovary
0.800
GeneticVariation
UNIPROT
The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer : no evidence for other ovarian cancer -susceptibility genes.
10486320
1999
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Malignant neoplasm of ovary
0.800
GeneticVariation
UNIPROT
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Malignant neoplasm of ovary
0.700
GeneticVariation
UNIPROT
Patterns of somatic mutation in human cancer genomes.
17344846
2007
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Malignant neoplasm of ovary
0.700
GeneticVariation
UNIPROT
Our study is the first direct evidence that PIK3CA is an oncogene in ovarian cancer and greatly extends recent findings in breast cancer.
15520168
2004
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Malignant neoplasm of ovary
0.700
GeneticVariation
UNIPROT
Lung cancer: intragenic ERBB2 kinase mutations in tumours.
15457249
2004
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of ovary
0.700
GeneticVariation
UNIPROT
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Malignant neoplasm of ovary
0.690
GeneticVariation
UNIPROT
×
Entrez Id:
4978
Gene Symbol:
OPCML
OPCML
Malignant neoplasm of ovary
0.610
GeneticVariation
UNIPROT
These findings suggest that OPCML is an excellent candidate for the 11q25 ovarian cancer TSG.
12819783
2003
×
Entrez Id:
673
Gene Symbol:
BRAF
BRAF
Malignant neoplasm of ovary
0.600
GeneticVariation
UNIPROT
×
Entrez Id:
22800
Gene Symbol:
RRAS2
RRAS2
Malignant neoplasm of ovary
0.600
GeneticVariation
UNIPROT
×
Entrez Id:
6794
Gene Symbol:
STK11
STK11
Malignant neoplasm of ovary
0.550
GeneticVariation
UNIPROT
×
Entrez Id:
8626
Gene Symbol:
TP63
TP63
Malignant neoplasm of ovary
0.530
GeneticVariation
UNIPROT
×
Entrez Id:
1801
Gene Symbol:
DPH1
DPH1
Malignant neoplasm of ovary
0.340
GeneticVariation
UNIPROT
×
Entrez Id:
4361
Gene Symbol:
MRE11
MRE11
Malignant neoplasm of ovary
0.320
GeneticVariation
UNIPROT
×
Entrez Id:
11170
Gene Symbol:
FAM107A
FAM107A
Malignant neoplasm of ovary
0.300
GeneticVariation
UNIPROT