|
rs11574311
|
|
AIDS related complex
|
|
0.020 |
GeneticVariation
|
BEFREE |
Based on single-locus analyses of the 18 SNPs examined, WRN-rs11574311 (T>C) was associated with ARC risk.
|
29689049 |
2018 |
|
rs1801131
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Haplotype analyses revealed an adverse effect of the haplotype "C-A-T-C" (alleles in order of SNPs rs3737967, rs1801131, rs1801133 and rs9651118) on ARC risk (OR = 1.55, P = 0.003).
|
26689687 |
2015 |
|
rs9651118
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Haplotype analyses revealed an adverse effect of the haplotype "C-A-T-C" (alleles in order of SNPs rs3737967, rs1801131, rs1801133 and rs9651118) on ARC risk (OR = 1.55, P = 0.003).
|
26689687 |
2015 |
|
rs1801133
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Haplotype analyses revealed an adverse effect of the haplotype "C-A-T-C" (alleles in order of SNPs rs3737967, rs1801131, rs1801133 and rs9651118) on ARC risk (OR = 1.55, P = 0.003).
|
26689687 |
2015 |
|
rs5881286
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Haplotype association including the - allele of rs5881286, C allele of rs2242318, and A allele of rs144581330 exhibited significantly higher distribution in the patients with ARC (p=8.0e-4; OR=3.38; 95% CI=1.66-6.87).
|
23882136 |
2013 |
|
rs2242318
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Haplotype association including the - allele of rs5881286, C allele of rs2242318, and A allele of rs144581330 exhibited significantly higher distribution in the patients with ARC (p=8.0e-4; OR=3.38; 95% CI=1.66-6.87).
|
23882136 |
2013 |
|
rs144581330
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Haplotype association including the - allele of rs5881286, C allele of rs2242318, and A allele of rs144581330 exhibited significantly higher distribution in the patients with ARC (p=8.0e-4; OR=3.38; 95% CI=1.66-6.87).
|
23882136 |
2013 |
|
rs4733220
|
|
AIDS related complex
|
|
0.020 |
GeneticVariation
|
BEFREE |
However, in MDR, the gene-gene interaction among the five SNPs (WRN-rs4733220 (G>A), WRN-rs1801195 (T>G), OGG1-rs2072668 (G>C) and OGG1-rs2304277 (A>G)) on ARC risk was significant (OR = 5.03, 95% CI: 3.54~7.13).
|
29689049 |
2018 |
|
rs1801195
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, in MDR, the gene-gene interaction among the five SNPs (WRN-rs4733220 (G>A), WRN-rs1801195 (T>G), OGG1-rs2072668 (G>C) and OGG1-rs2304277 (A>G)) on ARC risk was significant (OR = 5.03, 95% CI: 3.54~7.13).
|
29689049 |
2018 |
|
rs2072668
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, in MDR, the gene-gene interaction among the five SNPs (WRN-rs4733220 (G>A), WRN-rs1801195 (T>G), OGG1-rs2072668 (G>C) and OGG1-rs2304277 (A>G)) on ARC risk was significant (OR = 5.03, 95% CI: 3.54~7.13).
|
29689049 |
2018 |
|
rs2304277
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, in MDR, the gene-gene interaction among the five SNPs (WRN-rs4733220 (G>A), WRN-rs1801195 (T>G), OGG1-rs2072668 (G>C) and OGG1-rs2304277 (A>G)) on ARC risk was significant (OR = 5.03, 95% CI: 3.54~7.13).
|
29689049 |
2018 |
|
rs7154572
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the haplotypic analysis, the haplotypes consisting of rs7154572, rs7150141 and rs12432994 in Kinesin Light Chain 1 Gene (KLC1) showed significant association with ARC (p = 0.000878).
|
23776437 |
2013 |
|
rs7150141
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the haplotypic analysis, the haplotypes consisting of rs7154572, rs7150141 and rs12432994 in Kinesin Light Chain 1 Gene (KLC1) showed significant association with ARC (p = 0.000878).
|
23776437 |
2013 |
|
rs12432994
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the haplotypic analysis, the haplotypes consisting of rs7154572, rs7150141 and rs12432994 in Kinesin Light Chain 1 Gene (KLC1) showed significant association with ARC (p = 0.000878).
|
23776437 |
2013 |
|
rs2132397
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, three GJA8-tagged single nucleotide polymorphisms related to an increased ARC risk were identified: rs2132397 for general ARC under both dominant and additive models; rs7541950 for general ARC under both recessive and additive models; and rs6657114 for cortical cataract under the recessive model.
|
30349978 |
2018 |
|
rs7541950
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, three GJA8-tagged single nucleotide polymorphisms related to an increased ARC risk were identified: rs2132397 for general ARC under both dominant and additive models; rs7541950 for general ARC under both recessive and additive models; and rs6657114 for cortical cataract under the recessive model.
|
30349978 |
2018 |
|
rs6657114
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, three GJA8-tagged single nucleotide polymorphisms related to an increased ARC risk were identified: rs2132397 for general ARC under both dominant and additive models; rs7541950 for general ARC under both recessive and additive models; and rs6657114 for cortical cataract under the recessive model.
|
30349978 |
2018 |
|
rs4639
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Individuals carrying different rs4639 alleles had distinct <i>NEIL2</i> expression in lens capsule tissues from ARC cases and controls.
|
31253066 |
2019 |
|
rs2057768
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Less eczema was seen in individuals with the AA-genotype of rs2057768, and less ARC among those with the AA-genotype of rs2107356, especially ARC associated with sensitization to pollen.
|
20002627 |
2010 |
|
rs2107356
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Less eczema was seen in individuals with the AA-genotype of rs2057768, and less ARC among those with the AA-genotype of rs2107356, especially ARC associated with sensitization to pollen.
|
20002627 |
2010 |
|
rs2278414
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Moreover, the in vitro experiment indicated that miR-21-3p and miR-150-5p specifically downregulated luciferase reporter expression in the cell lines transfected with rs2278414 A allele compared with rs2278414 G. These results suggested that the association of SNP rs2278414 with ARC might involve an altered miRNA regulation of ZNF350.
|
27586871 |
2016 |
|
rs74641138
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our findings indicate that the genotype TC in polymorphism c.-4T>C and haplotype CCG of rs2269348, c.-4T>C, and rs74641138 in MIP may attach an additional genetic risk factor for ARC in Chinese.
|
21921980 |
2011 |
|
rs13181
|
|
AIDS related complex
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our meta-analysis suggested that the CC genotype of XPD Lys751Gln (A/C) SNP seemed to portend a decreased risk for ARC in Caucasian populations but not in Asian populations.
|
24906341 |
2014 |
|
rs1799782
|
|
AIDS related complex
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results indicated that both SNPs Arg194Trp in XRCC1 (P = 0.967) and Lys751Gln in XPD (P = 0.995) were not associated with ARC whether they were analyzed individually or in combined form (P > 0.05).
|
28560653 |
2018 |
|
rs1052133
|
|
AIDS related complex
|
|
0.020 |
GeneticVariation
|
BEFREE |
Regarding the OGG1-rs1052133, the GG (OR = 1.925; 95%CI, 1.181-3.136; p = 0.009) and CG (OR = 1.384; 95%CI, 1.171-1.636; p<0.001) genotypes indicated higher risk of ARC.
|
28253266 |
2017 |