Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2910164
rs2910164
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome
0.010 GeneticVariation BEFREE These findings indicate that miR-146a rs2910164 may act as a novel molecular marker for ACS s</span>usceptibility. 26537765

2015

dbSNP: rs2910164
rs2910164
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.010 GeneticVariation BEFREE A Genetic Variant in Pre-miR-146a (rs2910164 C>G) Is Associated with the Decreased Risk of Acute Coronary Syndrome in a Chinese Population. 26537765

2015

dbSNP: rs2910164
rs2910164
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease
0.020 GeneticVariation BEFREE In humans, the minor genotype of the single nucleotide polymorphism rs2910164 in HCT donors, which reduces expression of miR-146a, was associated with severe acute GVHD (grade III/IV). 25205119

2014

dbSNP: rs2910164
rs2910164
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease
0.020 GeneticVariation BEFREE We aim to analyze the association between NF-κB1 encoding p50 (rs28362491, -94 in.ertion/deletion ATTG) and miR-146a (rs2910164, G > C) polymorphisms and risk of aGVHD. 31813598

2019

dbSNP: rs2910164
rs2910164
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia
0.010 GeneticVariation BEFREE Haplotype analysis indicated a combination of allele A of rs57095329 and allele G of rs2910164 could represent a risk haplotype and an allele combination of G of rs57095329 and G of rs2910164 could represent a protective haplotype for ALL. 30576465

2019

dbSNP: rs2910164
rs2910164
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.010 GeneticVariation BEFREE miRNA-146a rs2910164 C>G polymorphism increased the risk of esophagogastric junction adenocarcinoma: a case-control study involving 2,740 participants. 29983589

2018

dbSNP: rs2910164
rs2910164
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder)
0.010 GeneticVariation BEFREE These findings suggest that miR-146a rs2910164C>G and miR-423 rs6505162C>A polymorphisms may contribute to genetic susceptibility to lung cancer and lung adenocarcinoma in Chinese non-smoking females. 26973201

2016

dbSNP: rs2910164
rs2910164
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
Adult Acute Lymphocytic Leukemia
0.010 GeneticVariation BEFREE Haplotype analysis indicated a combination of allele A of rs57095329 and allele G of rs2910164 could represent a risk haplotype and an allele combination of G of rs57095329 and G of rs2910164 could represent a protective haplotype for ALL. 30576465

2019

dbSNP: rs2910164
rs2910164
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma
0.010 GeneticVariation BEFREE MicroRNA-146a rs2910164 polymorphism and the risk of diffuse large B cell lymphoma in the Chinese Han population. 25370733

2014

dbSNP: rs2910164
rs2910164
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration
0.010 GeneticVariation BEFREE These analyses reported that the SNPs rs11671784 (<i>MIR27A</i>, G/A) and rs2910164 (<i>MIR146A</i>, C/G) were significantly associated with AMD risk. 30934838

2019

dbSNP: rs2910164
rs2910164
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder
0.010 GeneticVariation BEFREE This is the first genetic association study to explore the relationship of miRNA polymorphisms with AUDs and to show an association of the miR-146a C>G rs2910164 allelic variant with this disease. 24630744

2014

dbSNP: rs2910164
rs2910164
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.010 GeneticVariation BEFREE In the present study, the coding region of primary (pri)‑miR‑146a in patients with AD was scanned and the rare C allele of rs2910164 was found to be associated with AD. 26095531

2015

dbSNP: rs2910164
rs2910164
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.020 GeneticVariation BEFREE This is the first study to address the association between the miR-146a rs2910164G>C and miR-499 rs3746444T>C polymorphisms and AS, and it suggests a potential pathogenic factor for AS. 25836258

2015

dbSNP: rs2910164
rs2910164
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.020 GeneticVariation BEFREE And there was a significant association between miR-146a rs2910164(G/C) and PsA or AS. 31235484

2019

dbSNP: rs2910164
rs2910164
CUI: C0003165
Disease: Anthracosis
Anthracosis
0.010 GeneticVariation BEFREE In a case-control study of 496 CWP patients and 513 control subjects frequency matched by exposure years and work types, we genotyped four single-nucleotide polymorphisms (SNPs) (rs2910164, rs2292832, rs11614913 and rs3746444) in pre-miRNAs (miR-146a, miR-149, miR-196a2 and miR-499) and assessed the associations with risk of CWP. 19881472

2010

dbSNP: rs2910164
rs2910164
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.010 GeneticVariation BEFREE The association of the miRNA-146a polymorphism rs2910164 with atherosclerosis and restenosis was investigated. 25053223

2014

dbSNP: rs2910164
rs2910164
CUI: C0003864
Disease: Arthritis
Arthritis
0.020 GeneticVariation BEFREE But, we also find miRNA-146 rs2910164 and miRNA-499 rs3746444 polymorphism are associated with inflammatory arthritis in Middle East. 31223622

2019

dbSNP: rs2910164
rs2910164
CUI: C0003864
Disease: Arthritis
Arthritis
0.020 GeneticVariation BEFREE These findings did not support the genetic association between miR-146a rs2910164 (G/C) and JRA susceptibility, as well as the association of miR-196a-2 rs11614913 (C/T), miR-146a rs2431697, miR-146a rs57095329, miR-149 rs22928323 with arthritis. 31235484

2019

dbSNP: rs2910164
rs2910164
CUI: C0003872
Disease: Arthritis, Psoriatic
Arthritis, Psoriatic
0.020 GeneticVariation BEFREE The rs2910164 variant C-allele may play a role in the progression of PsA in the South African Indian population. 29587639

2018

dbSNP: rs2910164
rs2910164
CUI: C0003872
Disease: Arthritis, Psoriatic
Arthritis, Psoriatic
0.020 GeneticVariation BEFREE And there was a significant association between miR-146a rs2910164(G/C) and PsA or AS. 31235484

2019

dbSNP: rs2910164
rs2910164
CUI: C0004096
Disease: Asthma
Asthma
0.020 GeneticVariation BEFREE Our results provide evidence that rs2910164 may play a role in the susceptibility to childhood-onset asthma, but not SLE or JRA in Mexicans. 22823586

2012

dbSNP: rs2910164
rs2910164
CUI: C0004096
Disease: Asthma
Asthma
0.020 GeneticVariation BEFREE Our data indicate that rs2910164G/C and rs2292832C/T may play a role in the development of asthma. 21663520

2011

dbSNP: rs2910164
rs2910164
CUI: C0004096
Disease: Asthma
Asthma
0.020 GeneticVariation BEFREE We investigated the correlation between four SNPs (rs11614913, rs3746444, rs2910164, and rs229283) in pre-miRNAs and the risk of asthma in 220 asthma patients and 540 controls using polymerase chain reaction-restriction fragment length polymorphism methodology and DNA-sequencing. 21663520

2011

dbSNP: rs2910164
rs2910164
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.010 GeneticVariation BEFREE The association of the miRNA-146a polymorphism rs2910164 with atherosclerosis and restenosis was investigated. 25053223

2014

dbSNP: rs2910164
rs2910164
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.010 GeneticVariation BEFREE This study aims to evaluate the prognostic role and biological effect of functional MIR146A polymorphisms, rs2431697 and rs2910164, in non-valvular atrial fibrillation (AF) patients under oral anticoagulation.We studied 901 patients with permanent/paroxysmal AF stabilized for at least six months. 25008481

2014