|
rs2910164
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
In the subgroups, rs2910164 and rs3746444 were only associated with CVDs, especially CAD.
|
30642078 |
2019 |
|
rs2910164
|
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
<b>Conclusions:</b> The association of miR-146a rs2910164 (G/C) with RA was not found.
|
31235484 |
2019 |
|
rs2910164
|
|
Liver carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
We evaluated the associations of <i>miR-499A</i>>G (rs3746444), <i>miR-149C</i>>T (rs2292832), <i>miR-196a2T</i>>C (rs11614913), and <i>miR-146aG</i>>C (rs2910164) with HCC susceptibility in 100 HCC patients (70 males and 30 females) and 120 healthy controls (70 males and 50 females), using the PCR-restriction fragment length polymorphism method.
|
30215231 |
2019 |
|
rs2910164
|
|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In summary, miR-146a rs2910164 GC is significantly associated with BC in the Pakistani population.
|
30963551 |
2019 |
|
rs2910164
|
|
Liver carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Previous studies have shown that miRNA-146a rs2910164 polymorphism can be associated with the pathogenesis of liver diseases such as hepatocellular carcinoma.
|
30624803 |
2019 |
|
rs2910164
|
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
In summary, miR-146a rs2910164 GC is significantly associated with BC in the Pakistani population.
|
30963551 |
2019 |
|
rs2910164
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
Subgroup analyses based on ethnicity, source of control group, and country indicated that there were strong associations between miRNA-146a rs2910164 and cancer risk.
|
29750042 |
2018 |
|
rs2910164
|
|
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
MiR-146a rs2910164 polymorphism might be associated with the susceptibility to lung cancer and nasopharyngeal carcinoma.
|
29127520 |
2018 |
|
rs2910164
|
|
Carcinoma of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
These findings suggested that SNPs rs71428439 (miR-149), rs2910164 (miR-146a), rs928508 (mir-30c-1) and rs629367 (let-7a-2) were associated with the lung cancer prevalence, polymorphisms of rs11614913 (miR-196a-2) and rs9280508 (miR-30c-1) significantly influenced the patients' response to platinum-based chemotherapy, which may serve as potential clinical biomarkers to predict lung cancer risk and platinum-based chemotherapy response.
|
30069329 |
2018 |
|
rs2910164
|
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Conclusion Our data indicate that miR-146a (rs2910164</span>) and miR-27a (rs895819) variants contribute to breast cancer.
|
29521182 |
2018 |
|
rs2910164
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
MiR-146a rs2910164 polymorphism and overall cancer susceptibility were significantly uncorrelated in all genetic models.
|
29127520 |
2018 |
|
rs2910164
|
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Hsa-mir-149C/T rs2292832 and hsa-mir-146a G/C rs2910164 may influence CRC risk in an ethnicity-dependent manner by interfering with CRC progression parameters in Tunisian cohort.
|
29715515 |
2018 |
|
rs2910164
|
|
Malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
The results indicated that lung cancer risk was significantly associated with miRNA-196a2 rs11614913 and miRNA-146a rs2910164.
|
29750042 |
2018 |
|
rs2910164
|
|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Thus, the present study explored the association between five common functional polymorphisms in miRNAs (i.e., miRNA-196a2C>T, rs11614913; miRNA-146aG>C, rs2910164; miRNA-423C>A, rs6505162; miRNA-608G>C, rs4919510; miRNA-27aC>T, rs895819) and the risk of BC.
|
29782194 |
2018 |
|
rs2910164
|
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Serum miRNA-146a was negatively correlated with anti-nuclear antibodies (ANA). miRNA-146a (rs2910164) genotyping revealed that the GG genotype and the frequency of the G allele were significantly higher in RA patients compared to the controls. miRNA-499 (rs3746444), genotyping revealed that the CC genotype and the frequency of the C allele were significantly higher.
|
29700729 |
2018 |
|
rs2910164
|
|
Malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
These findings suggested that SNPs rs71428439 (miR-149), rs2910164 (miR-146a), rs928508 (mir-30c-1) and rs629367 (let-7a-2) were associated with the lung cancer prevalence, polymorphisms of rs11614913 (miR-196a-2) and rs9280508 (miR-30c-1) significantly influenced the patients' response to platinum-based chemotherapy, which may serve as potential clinical biomarkers to predict lung cancer risk and platinum-based chemotherapy response.
|
30069329 |
2018 |
|
rs2910164
|
|
Malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
MiR-146a rs2910164 polymorphism might be associated with the susceptibility to lung cancer and nasopharyngeal carcinoma.
|
29127520 |
2018 |
|
rs2910164
|
|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
miRNA 196a2(rs11614913) & 146a(rs2910164) polymorphisms & breast cancer risk for women in an Iranian population.
|
29965793 |
2018 |
|
rs2910164
|
|
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
The results indicated that lung cancer risk was significantly associated with miRNA-196a2 rs11614913 and miRNA-146a rs2910164.
|
29750042 |
2018 |
|
rs2910164
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
Subgroup analyses based on ethnicity, source of control group, and country indicated that there were strong associations between miRNA-146a rs2910164 and cancer risk.
|
29750042 |
2018 |
|
rs2910164
|
|
Carcinoma of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
MiR-146a rs2910164 polymorphism might be associated with the susceptibility to lung cancer and nasopharyngeal carcinoma.
|
29127520 |
2018 |
|
rs2910164
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
MiR-146a rs2910164 polymorphism and overall cancer susceptibility were significantly uncorrelated in all genetic models.
|
29127520 |
2018 |
|
rs2910164
|
|
Rheumatoid Arthritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
<b>Significance:</b> The miR-146a rs2910164 G > C polymorphism was not associated with susceptibility to RA.
|
30498453 |
2018 |
|
rs2910164
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
In addition, the presence of a minor allele of the rs2910164 polymorphism was significantly associated with risk of depression in patients with CAD.
|
29749487 |
2018 |
|
rs2910164
|
|
Liver carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In the subgroup analysis for cancer types, miR-146a rs2910164 polymorphism was associated with the susceptibility of lung cancer (CC vs. GG: OR 1.275, 95% CI 1.117-1.455 (P = 0.000); CC + CG vs. GG: OR 1.166, 95% CI 1.052-1.293 (P = 0.003); CC vs. CG + GG: OR 1.239, 95% CI 1.116-1.375 (P = 0.000); C vs. G OR 1.151, 95% CI 1.080-1.227 (P = 0.000)) and nasopharyngeal carcinoma (CC vs. GG: OR 1.713, 95% CI 1.183-2.479 (P = 0.004); CC vs. CG + GG: OR 1.672, 95% CI 1.330-2.103 (P = 0.000); C vs. G: OR 1.400, 95% CI 1.181-1.659 (P = 0.000)), but it was not associated with hepatocellular carcinoma and gastric cancer.
|
29127520 |
2018 |