Source: GWASCAT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2542151
rs2542151
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.880 GeneticVariation GWASCAT Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300

2007
dbSNP: rs2542151
rs2542151
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.880 GeneticVariation GWASCAT Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. 17554261

2007
dbSNP: rs2542151
rs2542151
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.880 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394

2008
dbSNP: rs3024505
rs3024505
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.850 GeneticVariation GWASCAT Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463

2010
dbSNP: rs3024505
rs3024505
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.850 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919

2015
dbSNP: rs3024505
rs3024505
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.850 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908

2017
dbSNP: rs13361189
rs13361189
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.850 GeneticVariation GWASCAT Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. 17554261

2007
dbSNP: rs10758669
rs10758669
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		C 0.850 GeneticVariation GWASCAT Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463

2010
dbSNP: rs10758669
rs10758669
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.850 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs10758669
rs10758669
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		C 0.850 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394

2008
dbSNP: rs7869487
rs7869487
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.830 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919

2015
dbSNP: rs9271366
rs9271366
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		C 0.820 GeneticVariation GWASCAT The comparative GWAS and the replication study identified significant associations in the major histocompatibility complex region at 6p21 with UC and CD (rs9271366, P = 1.6 × 10⁻⁷⁰; odds ratio [OR] = 4.44). 21699788

2011
dbSNP: rs9271366
rs9271366
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.820 GeneticVariation GWASCAT Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations. 23850713

2014
dbSNP: rs6478106
rs6478106
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.820 GeneticVariation GWASCAT We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)). 23266558

2013
dbSNP: rs4409764
rs4409764
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.820 GeneticVariation GWASCAT We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15. 25489960

2015
dbSNP: rs4409764
rs4409764
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.820 GeneticVariation GWASCAT Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463

2010
dbSNP: rs4409764
rs4409764
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.820 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908

2017
dbSNP: rs4409764
rs4409764
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.820 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919

2015
dbSNP: rs2872507
rs2872507
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.820 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394

2008
dbSNP: rs2872507
rs2872507
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.820 GeneticVariation GWASCAT Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463

2010
dbSNP: rs7927894
rs7927894
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.810 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394

2008
dbSNP: rs7765379
rs7765379
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.810 GeneticVariation GWASCAT We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)). 23266558

2013
dbSNP: rs7746082
rs7746082
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		C 0.810 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919

2015
dbSNP: rs7746082
rs7746082
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		C 0.810 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394

2008
dbSNP: rs7746082
rs7746082
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.810 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908

2017