Source: CURATED

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1006737
rs1006737
CACNA1C
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.900 GeneticVariation GWASCAT Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. 23453885

2013
dbSNP: rs1006737
rs1006737
CACNA1C
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.900 GeneticVariation GWASCAT Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. 20351715

2011
dbSNP: rs1006737
rs1006737
CACNA1C
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		A 0.900 GeneticVariation GWASDB Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. 20351715

2011
dbSNP: rs2535629
rs2535629
ITIH3
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		A 0.820 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913

2019
dbSNP: rs2535629
rs2535629
ITIH3
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.820 GeneticVariation GWASDB In the MDD-bipolar cross-disorder analysis, 15 SNPs exceeded genome-wide significance (P<5 × 10(-8)), and all were in a 248 kb interval of high LD on 3p21.1 (chr3:52 425 083-53 822 102, minimum P=5.9 × 10(-9) at rs2535629). 22472876

2013
dbSNP: rs2535629
rs2535629
ITIH3
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.820 GeneticVariation GWASCAT Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. 23453885

2013
dbSNP: rs7647854
rs7647854
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		G 0.810 GeneticVariation GWASCAT We identified one replicated genome-wide significant locus associated with adult-onset (>27 years) MDD (rs7647854, odds ratio: 1.16, 95% confidence interval: 1.11-1.21, p = 5.2 × 10<sup>-11</sup>). 27519822

2017
dbSNP: rs7647854
rs7647854
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.810 GeneticVariation GWASDB A mega-analysis of genome-wide association studies for major depressive disorder. 22472876

2013
dbSNP: rs10065906
rs10065906
LOC105377684
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		C 0.800 GeneticVariation GWASCAT Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. 23377640

2013
dbSNP: rs10065906
rs10065906
LOC105377684
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		C 0.800 GeneticVariation GWASDB Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. 23377640

2013
dbSNP: rs10484358
rs10484358
GMPR
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		T 0.800 GeneticVariation GWASDB Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. 23377640

2013
dbSNP: rs10484358
rs10484358
GMPR
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		T 0.800 GeneticVariation GWASCAT Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. 23377640

2013
dbSNP: rs10774037
rs10774037
CACNA1C
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		A 0.800 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913

2019
dbSNP: rs10774037
rs10774037
CACNA1C
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.800 GeneticVariation GWASDB A mega-analysis of genome-wide association studies for major depressive disorder. 22472876

2013
dbSNP: rs10994338
rs10994338
ANK3
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		A 0.800 GeneticVariation GWASDB Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. 20351715

2011
dbSNP: rs10994338
rs10994338
ANK3
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.800 GeneticVariation GWASCAT Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. 20351715

2011
dbSNP: rs11773103
rs11773103
DMTF1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		G 0.800 GeneticVariation GWASDB Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. 20351715

2011
dbSNP: rs11773103
rs11773103
DMTF1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.800 GeneticVariation GWASCAT Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. 20351715

2011
dbSNP: rs12054895
rs12054895
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		T 0.800 GeneticVariation GWASDB Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. 23377640

2013
dbSNP: rs12054895
rs12054895
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		T 0.800 GeneticVariation GWASCAT Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. 23377640

2013
dbSNP: rs12410462
rs12410462
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		A 0.800 GeneticVariation GWASCAT Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. 23377640

2013
dbSNP: rs12410462
rs12410462
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		A 0.800 GeneticVariation GWASDB Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. 23377640

2013
dbSNP: rs12446956
rs12446956
ZFHX3 ; LINC01568
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		C 0.800 GeneticVariation GWASCAT Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. 21042317

2012
dbSNP: rs12446956
rs12446956
ZFHX3 ; LINC01568
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		C 0.800 GeneticVariation GWASDB Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. 21042317

2012
dbSNP: rs12912251
rs12912251
LINC02694
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		T 0.800 GeneticVariation GWASDB Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. 20351715

2011