|
rs1217691063
|
|
Atherothrombosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
The methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms, which are associated with hyperhomocysteinemia and nitric oxide (NO) deficiency (which is related to atherothrombosis and cerebral ischemia), have not been studied in moyamoya disease.
|
25098357 |
2014 |
|
rs1217691063
|
|
Atherothrombosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Elevation in homocysteine and methylenetetrahydrofolate reductase (MTHFR) gene variants, C677T and A1298C, have been linked with atherothrombosis.
|
18204887 |
2009 |
|
rs1217691063
|
|
Atherothrombosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
We report a case of myocardial infarction at a young age in a subject heterozygous for the G20210A prothrombin gene variant and homozygous for the C677T MTHFR polymorphism, who presented a strong family history of atherothrombosis.
|
17920139 |
2008 |
|
rs397507444
|
|
Atherothrombosis
|
|
0.020 |
GeneticVariation
|
BEFREE |
The methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms, which are associated with hyperhomocysteinemia and nitric oxide (NO) deficiency (which is related to atherothrombosis and cerebral ischemia), have not been studied in moyamoya disease.
|
25098357 |
2014 |
|
rs397507444
|
|
Atherothrombosis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Elevation in homocysteine and methylenetetrahydrofolate reductase (MTHFR) gene variants, C677T and A1298C, have been linked with atherothrombosis.
|
18204887 |
2009 |
|
rs1061170
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In contrast to expected results, we found no association of Y402H polymorphism with risk of atherothrombosis (adjusted: myocardial infarction, OR=1.09, 95%CI 0.88-1.36, p=0.43; ischaemic stroke, OR=1.11, 95%CI 0.81-1.54, p=0.52; venous thromboembolism, OR=1.41, 95%CI 0.88-2.24, p=0.15), nor with baseline plasma C-reactive protein levels [median (interquartile range) mg/L: YY, 1.39 (0.70-2.60); YH, 1.10 (0.57-2.16); HH, 1.00 (0.48-1.79); p=0.14].
|
16229850 |
2006 |
|
rs1188383936
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We report a case of myocardial infarction at a young age in a subject heterozygous for the G20210A prothrombin gene variant and homozygous for the C677T MTHFR polymorphism, who presented a strong family history of atherothrombosis.
|
17920139 |
2008 |
|
rs1194897557
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Mutations in methylenetetrahydrofolate reductase (C667T), cystathionine beta-synthase (T833C), and methionine synthase (A2756G) genes cause hyperhomocysteinemia, an independent risk factor for atherothrombosis.
|
12476935 |
2002 |
|
rs1805087
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Mutations in methylenetetrahydrofolate reductase (C667T), cystathionine beta-synthase (T833C), and methionine synthase (A2756G) genes cause hyperhomocysteinemia, an independent risk factor for atherothrombosis.
|
12476935 |
2002 |
|
rs2454727
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Coding variants, rs7314976 (p.R311C) and rs2454727 (p.M317I), were genotyped in 2067 participants from the Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides and Impact on Global Health Outcomes (AIM-HIGH) trial.
|
28628560 |
2017 |
|
rs4986790
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Toll-like receptor 4 Asp299Gly gene polymorphism and risk of atherothrombosis.
|
15576653 |
2005 |
|
rs5742905
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Mutations in methylenetetrahydrofolate reductase (C667T), cystathionine beta-synthase (T833C), and methionine synthase (A2756G) genes cause hyperhomocysteinemia, an independent risk factor for atherothrombosis.
|
12476935 |
2002 |
|
rs662
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Paraoxonase 1 L55M, Q192R and paraoxonase 2 S311C alleles in atherothrombosis.
|
23225229 |
2013 |
|
rs7080536
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In clinical studies, the G534E single nucleotide polymorphism (Marburg I) of FSAP has been linked to late complications of atherothrombosis and is associated with a low proteolytic activity, particularly, towards pro-uPA.
|
18278176 |
2008 |
|
rs7314976
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Coding variants, rs7314976 (p.R311C) and rs2454727 (p.M317I), were genotyped in 2067 participants from the Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides and Impact on Global Health Outcomes (AIM-HIGH) trial.
|
28628560 |
2017 |
|
rs7493
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Paraoxonase 1 L55M, Q192R and paraoxonase 2 S311C alleles in atherothrombosis.
|
23225229 |
2013 |
|
rs769737896
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Mutations in methylenetetrahydrofolate reductase (C667T), cystathionine beta-synthase (T833C), and methionine synthase (A2756G) genes cause hyperhomocysteinemia, an independent risk factor for atherothrombosis.
|
12476935 |
2002 |
|
rs773371778
|
|
Atherothrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Mutations in methylenetetrahydrofolate reductase (C667T), cystathionine beta-synthase (T833C), and methionine synthase (A2756G) genes cause hyperhomocysteinemia, an independent risk factor for atherothrombosis.
|
12476935 |
2002 |