Source: CURATED

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs145518263
rs145518263
ADAM10
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.800 GeneticVariation UNIPROT ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function. 24055016

2013
dbSNP: rs145518263
rs145518263
ADAM10
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.800 GeneticVariation UNIPROT Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity. 19608551

2009
dbSNP: rs145518263
rs145518263
ADAM10
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		C 0.800 SusceptibilityMutation CLINVAR

dbSNP: rs483352912
rs483352912
ADAM10
CUI: C0406811
Disease: Reticulate acropigmentation of Kitamura
Reticulate acropigmentation of Kitamura 		0.800 GeneticVariation UNIPROT Whole-exome sequencing identifies ADAM10 mutations as a cause of reticulate acropigmentation of Kitamura, a clinical entity distinct from Dowling-Degos disease. 23666529

2013
dbSNP: rs483352912
rs483352912
ADAM10
CUI: C0406811
Disease: Reticulate acropigmentation of Kitamura
Reticulate acropigmentation of Kitamura 		A 0.800 CausalMutation CLINVAR

dbSNP: rs483352916
rs483352916
ADAM10
CUI: C0406811
Disease: Reticulate acropigmentation of Kitamura
Reticulate acropigmentation of Kitamura 		0.800 GeneticVariation UNIPROT Whole-exome sequencing identifies ADAM10 mutations as a cause of reticulate acropigmentation of Kitamura, a clinical entity distinct from Dowling-Degos disease. 23666529

2013
dbSNP: rs483352916
rs483352916
ADAM10
CUI: C0406811
Disease: Reticulate acropigmentation of Kitamura
Reticulate acropigmentation of Kitamura 		T 0.800 CausalMutation CLINVAR

dbSNP: rs61751103
rs61751103
ADAM10
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.800 GeneticVariation UNIPROT ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function. 24055016

2013
dbSNP: rs61751103
rs61751103
ADAM10
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.800 GeneticVariation UNIPROT Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity. 19608551

2009
dbSNP: rs61751103
rs61751103
ADAM10
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		G 0.800 SusceptibilityMutation CLINVAR

dbSNP: rs11638416
rs11638416
ADAM10
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs12911832
rs12911832
ADAM10 ; HSP90AB4P
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		A 0.700 GeneticVariation GWASCAT Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect. 30285260

2019
dbSNP: rs12911832
rs12911832
ADAM10 ; HSP90AB4P
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		A 0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia. 28991256

2017
dbSNP: rs16940571
rs16940571
ADAM10
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs17269425
rs17269425
ADAM10
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs267604273
rs267604273
ADAM10
CUI: C1321872
Disease: Stage IV Skin Melanoma
Stage IV Skin Melanoma 		0.700 GeneticVariation UNIPROT

dbSNP: rs347118
rs347118
ADAM10
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs347122
rs347122
ADAM10
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs387005
rs387005
ADAM10
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs4238331
rs4238331
ADAM10
CUI: C1305855
Disease: Body mass index
Body mass index 		T 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127

2018
dbSNP: rs424346
rs424346
ADAM10
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs437549
rs437549
ADAM10
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs442495
rs442495
ADAM10
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		C 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk. 30617256

2019
dbSNP: rs483352913
rs483352913
ADAM10
CUI: C0406811
Disease: Reticulate acropigmentation of Kitamura
Reticulate acropigmentation of Kitamura 		T 0.700 CausalMutation CLINVAR

dbSNP: rs483352914
rs483352914
ADAM10
CUI: C0406811
Disease: Reticulate acropigmentation of Kitamura
Reticulate acropigmentation of Kitamura 		T 0.700 CausalMutation CLINVAR